Evidence map›Paper›PMID 33437604›Full record

ArticleTaiwan journal of ophthalmology

A novel G26A variation in 5' half of TGIF1 gene associates with high myopia in ethnic Kashmiri population from India.

Shabhat Rasool, Rubiya Dar, Arif Akbar Bhat, Shiekh Gazalla Ayub, Muneeb U Rehman, Sabia Rashid, Tariq Jan, Khursheed Iqbal Andrabi

Abstract read
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In one paragraph

Article in Taiwan journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Shabhat RasoolDepartment of Biotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, India.
Rubiya DarDepartment of Biotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, India.
Arif Akbar BhatDepartment of Biochemistry, Government Medical College, Srinagar, Jammu and Kashmir, India.
Shiekh Gazalla AyubDepartment of Biotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, India.
Muneeb U RehmanDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Sabia RashidDepartment of Ophthalmology, Government Medical College, Srinagar, Jammu and Kashmir, India.
Tariq JanDepartment of Statistics, University of Kashmir, Srinagar, Jammu and Kashmir, India.
Khursheed Iqbal AndrabiDepartment of Biotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to look at novel variations in TGIF1 gene and explores their potential association with high myopia in an ethnic population from Kashmir (India). Genomic DNA was genotyped for polymorphic variations, and allele frequencies were tested for the Hardy-Weinberg disequilibrium in 240 ethnic Kashmiri cases with high myopia with a spherical equivalent of >-6 diopters (D) and compared with emmetropic controls with spherical equivalent within -0.5D in one or both eyes represented by a sample size of 228. In this study, we found a novel sequence variation G26A (GAT to AAT) in 5' half of TGIF1 gene (p. aspartic acid >asparagine) at a frequency of 62% (148/240,

Indexed as

EthnicgenemyopianovelTG1F1variation

Identifiers

PMID33437604
PMCPMC7787093

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