ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020
Nanocomposite Hydrogel with Tantalum Microparticles for Rapid Endovascular Hemostasis.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 62 citations in OpenAlex.
- Tantalum-Based Nanomaterials: From Properties to Biomedical Applications.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Preoperative Embolization of a Spinal Metastasis With Obsidio Conformable Embolic: A Case Report.Stroke (Hoboken, N.J.) · 2026Article
- Mapping the research landscape of nanotechnology based immunotherapy for hepatocellular carcinoma.Discover oncology · 2025Article
- Interfacial Roughness-Reinforced Magnetic Nanosheet Colloidal Gels for Stable Embolization and Magnetothermal Therapy of Hepatic Tumor.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Interventional Radiology Management of Vascular Trauma in the Pelvis: Literature, Current Practice, and Strategies for the Future.Seminars in interventional radiology · 2025Review
- Real-world clinical experience with Obsidio Conformable Embolic.CVIR endovascular · 2025Article
- Catheter Injectable Multifunctional Biomaterial for the Treatment of Infected Enterocutaneous Fistulas.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A Single Institution Experience with a Shear-Thinning Conformable Embolic for Endovascular Embolization.Cardiovascular and interventional radiology · 2025Article
- Early Experience Using Tantalum-Loaded Nanocomposite Hydrogel Conformable Embolic for Upper Gastrointestinal Bleeding-Open-Sandwich Technique.Journal of clinical medicine · 2025Article
- Optimal combination of microcoils, flow control, and n-butyl cyanoacrylate-Lipiodol-iopamidol (2:3:1) for feasible embolization of medium-sized arteries in an in vitro vascular model.Japanese journal of radiology · 2025Article
- A soft thermal sensor for the continuous assessment of flow in vascular access.Nature communications · 2025Article
- Technical and Clinical Outcomes of Embolization of Hypervascular Renal Tumors Using Tantalum-Loaded Obsidio Conformable Embolic (Ta-OCE): a single-center experience.CVIR oncology · 2025Article
- Advancements in Nanomedicine for the Diagnosis and Treatment of Kidney Stones.International journal of nanomedicine · 2025Review
- Mechanical investigation of a Tandem embolization-visualization system for minimally invasive procedures.Journal of the mechanical behavior of biomedical materials · 2024Article
- A novel conformable embolic for selective transarterial embolization of acute hemorrhages: a technical note.CVIR endovascular · 2024Article
- Percutaneous Delivery of Oncogel for Targeted Liver Tumor Ablation and Controlled Release of Therapeutics.Advanced materials (Deerfield Beach, Fla.) · 2024Article
- An Investigation on the Effect of Contrast Agents in the Chitosan-Nanoclay Shear Thinning Hydrogel for Trans-Catheter Arterial Embolization.JOM (Warrendale, Pa. : 1989) · 2024Article
- Biocompatible Liquid Embolic for the Treatment of Microvascular Hemorrhage.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Chitosan-nanoclay embolic material for catheter-directed arterial embolization.Journal of biomedical materials research. Part A · 2024Article
- OnyxGels (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Endovascular embolization to treat vascular hemorrhage involves pushing coil-shaped metal wires into the artery repeatedly until they are densely packed to slow the blood flow and clot. However, coil embolization is associated with high rebleeding rates, unpredictable economics and, most importantly, they rely on the patient's ability to make a clot. These issues are exacerbated when the patient is anticoagulated or coagulopathic. A novel bioengineered tantalum-loaded nanocomposite hydrogel for gel embolic material (Ta-GEM) that can be rapidly delivered using clinical catheters for instant hemostasis regardless of the coagulopathic state is reported. Ta-GEM formulation is visible by most of the clinically available imaging modalities including ultrasound, computed tomography, magnetic resonance imaging, and fluoroscopy without significant artifact. In addition, Ta-GEM can be retrieved, allowing temporary vascular occlusion, and it can be used to rescue cases of failed coil embolization. Ta-GEM occlusion of first-order arteries such as the renal artery and iliac artery in a swine model is found to be safe and durable; by 28 days, 75% of the injected Ta-GEM in the arterial lumen is replaced by dense connective tissue. Altogether, this study demonstrates that Ta-GEM has many advantages over the current technologies and has potential applications in clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.