Evidence map›Paper›PMID 33437501›Full record

ArticleFuture science OA2020

Point-of-use sweat biosensor to track the endocrine-inflammation relationship for chronic disease monitoring.

Sayali Upasham, Ashlesha Bhide, Kai-Chun Lin, Shalini Prasad

Abstract read
In one paragraph

Article in Future science OA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sayali UpashamDepartment of Bioengineering, University of Texas at Dallas, Richardson, TX 75080, USA.ORCID https://orcid.org/0000-0002-3043-2010
Ashlesha BhideDepartment of Bioengineering, University of Texas at Dallas, Richardson, TX 75080, USA.
Kai-Chun LinDepartment of Bioengineering, University of Texas at Dallas, Richardson, TX 75080, USA.
Shalini PrasadDepartment of Bioengineering, University of Texas at Dallas, Richardson, TX 75080, USA.ORCID https://orcid.org/0000-0002-2404-3801

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe hypothalamic-pituitary-adrenal axis is involved in maintaining homeostasis by engaging with the parasympathetic nervous system. During the process of disease affliction, this relationship is disturbed and there is an imbalance driven response observed. MATERIALS &

methodsBy monitoring the two key components involved in these pathways, cortisol and TNF-α, the manifestations of chronic stress on the body's homeostasis can be evaluated in a comprehensive manner. This work highlights the development of an electrochemical detection system for the two biomarkers through human sweat.

resultsLimit of detection and dynamic ranges are 1 ng/ml, 1-200 ng/ml for cortisol and 1 pg/ml, 1-1000 pg/ml for TNF-α.

conclusionThis wearable system is designed to be a point of use, chronic disease self-monitoring and management platform.

Indexed as

biosensorcortisolelectrochemicalendocrineinflammationsweattumor necrosis factor-α

Identifiers

PMID33437501
PMCPMC7787138

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.