Evidence map›Paper›PMID 33437362›Full record

ArticleAmerican journal of translational research2020

Polydopamine coating with static magnetic field promotes the osteogenic differentiation of human bone-derived mesenchymal stem cells on three-dimensional printed porous titanium scaffolds by upregulation of the BMP-Smads signaling pathway.

Lingpeng Kong, Yong Han, Qingsen Lu, Dongsheng Zhou, Bomin Wang, Dawei Wang, Wupeng Zhang, Hao Xiang, Mingzhen Li, Fu Wang

Abstract read
In one paragraph

Article in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lingpeng KongDepartment of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University No. 324, Jingwu Road, Jinan 250021, Shandong, P. R. China.
Yong HanDepartment of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University No. 324, Jingwu Road, Jinan 250021, Shandong, P. R. China.
Qingsen LuDepartment of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University No. 324, Jingwu Road, Jinan 250021, Shandong, P. R. China.
Dongsheng ZhouDepartment of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University No. 324, Jingwu Road, Jinan 250021, Shandong, P. R. China.
Bomin WangDepartment of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University No. 324, Jingwu Road, Jinan 250021, Shandong, P. R. China.
Dawei WangDepartment of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University No. 324, Jingwu Road, Jinan 250021, Shandong, P. R. China.
Wupeng ZhangDepartment of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University No. 324, Jingwu Road, Jinan 250021, Shandong, P. R. China.
Hao XiangDepartment of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University No. 324, Jingwu Road, Jinan 250021, Shandong, P. R. China.
Mingzhen LiDepartment of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University No. 324, Jingwu Road, Jinan 250021, Shandong, P. R. China.
Fu WangDepartment of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University No. 324, Jingwu Road, Jinan 250021, Shandong, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone regeneration has always been a hot topic for orthopedic surgeons. The role of polydopamine coating in promoting bone regeneration has attracted much attention. Static magnetic field (SMF) is considered an effective and noninvasive treatment for enhancing bone regeneration. However, the effect of polydopamine combined with SMF on bone regeneration on scaffolds is not clear. The aim of this study was to investigate the effects and potential mechanism of polydopamine coating combined with SMF on bone regeneration in three-dimensional printed scaffolds. The polydopamine coating (pTi group) was applied onto porous Ti6Al4V scaffolds (Ti group). Surface characterization was performed by scanning electron microscopy. The 100 mT SMF environment (pTi-SMF group) was established to enhance osteogenic differentiation of human bone-derived mesenchymal stem cells (hBMSCs) on polydopamine coating scaffolds. The cell viability and proliferation were significantly enhanced in the SMF environment (pTi-SMF

Indexed as

Osteogenesispolydopaminestatic magnetic fieldthree-dimensional printingtitanium alloy scaffold

Identifiers

PMID33437362
PMCPMC7791488

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.