Evidence map›Paper›PMID 33437186›Full record

ReviewCentral-European journal of immunology2020

Secondary immunodeficiencies with predominant antibody deficiency: multidisciplinary perspectives of Polish experts.

Karina Jahnz-RÓŻyk, Ewa WiĘsik-Szewczyk, Jacek RoliŃski, Maciej Siedlar, WiesŁaw JĘdrzejczak, Wojciech Sydor, Agnieszka Tomaszewska

Abstract readReview
In one paragraph

Review in Central-European journal of immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karina Jahnz-RÓŻykDepartment of Internal Medicine, Pneumonology, Allergology and Clinical Immunology, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine, Warsaw, Poland.
Ewa WiĘsik-SzewczykDepartment of Internal Medicine, Pneumonology, Allergology and Clinical Immunology, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine, Warsaw, Poland.
Jacek RoliŃskiDepartment of Clinical Immunology, Medical University of Lublin, Lublin, Poland.
Maciej SiedlarDepartment of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Krakow, Poland.
WiesŁaw JĘdrzejczakDepartment of Hematology, Oncology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.
Wojciech SydorDepartment of Rheumatology and Immunology, Jagiellonian University Medical College, Krakow, Poland.
Agnieszka TomaszewskaDepartment of Hematology, Oncology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At present, secondary immune deficiencies have become a clinical problem, recognized in different specialties. The aim of this paper was to increase awareness and support the need for screening at-risk populations. Secondary immune deficiencies result in variety of conditions, but not all of them require immunoglobulin replacement therapy, as specific antibody response might be preserved. Moreover, the management of secondary immune deficiencies vary between countries and different medical disciplines. This literature review presents the most common causes and clinical presentation of secondary immunodeficiencies with predominant impaired antibody production. We present diagnostic guidelines for patients at-risk, with an emphasis on the role of prophylactic vaccination as a treatment and diagnostic tool. This review considers the specificity and disparities of the Polish healthcare system and ultimately, suggests that management teams should include a clinical immunologist experienced in the treatment of humoral immunodeficiencies.

Indexed as

antibody deficiencydiagnostic workupimmunoglobulin substitutionrituximabsecondary hypogammaglobulinemiasubcutaneous immunoglobulin

Identifiers

PMID33437186
PMCPMC7790006

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.