Evidence map›Paper›PMID 33436985›Full record

ArticleScientific reports2021

Antiviral activity of lambda-carrageenan against influenza viruses and severe acute respiratory syndrome coronavirus 2.

Yejin Jang, Heegwon Shin, Myoung Kyu Lee, Oh Seung Kwon, Jin Soo Shin, Yong-Il Kim, Chan Woo Kim, Hye-Ra Lee, Meehyein Kim

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Review
  6. Antiviral Activity ofPathogens (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. EPS T14 fromImmunoTargets and therapy · 2024
    Article
  19. Review
  20. Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yejin JangInfectious Diseases Therapeutic Research Center, Korea Research Institute of Chemical Technology (KRICT), 141 Gajeongro, Yuseong, Daejeon, 34114, Republic of Korea.
Heegwon ShinDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.
Myoung Kyu LeeInfectious Diseases Therapeutic Research Center, Korea Research Institute of Chemical Technology (KRICT), 141 Gajeongro, Yuseong, Daejeon, 34114, Republic of Korea.
Oh Seung KwonInfectious Diseases Therapeutic Research Center, Korea Research Institute of Chemical Technology (KRICT), 141 Gajeongro, Yuseong, Daejeon, 34114, Republic of Korea.
Jin Soo ShinInfectious Diseases Therapeutic Research Center, Korea Research Institute of Chemical Technology (KRICT), 141 Gajeongro, Yuseong, Daejeon, 34114, Republic of Korea.
Yong-Il KimHanmi Pharmaceutical Co., Hwaseong-si, Gyeonggi-do, 18536, Republic of Korea.
Chan Woo KimDepartment of Biotechnology and Bioinformatics, College of Science and Technology, Korea University, Sejong, 30019, Republic of Korea.
Hye-Ra LeeDepartment of Biotechnology and Bioinformatics, College of Science and Technology, Korea University, Sejong, 30019, Republic of Korea.
Meehyein KimInfectious Diseases Therapeutic Research Center, Korea Research Institute of Chemical Technology (KRICT), 141 Gajeongro, Yuseong, Daejeon, 34114, Republic of Korea. mkim@krict.re.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza virus and coronavirus, belonging to enveloped RNA viruses, are major causes of human respiratory diseases. The aim of this study was to investigate the broad spectrum antiviral activity of a naturally existing sulfated polysaccharide, lambda-carrageenan (λ-CGN), purified from marine red algae. Cell culture-based assays revealed that the macromolecule efficiently inhibited both influenza A and B viruses with EC

Indexed as

COVID-19 Drug TreatmentAnimalsAntiviral AgentsCarrageenanDogsFemaleHEK293 CellsHumansMadin Darby Canine Kidney CellsMiceMice, Inbred BALB COrthomyxoviridaeOrthomyxoviridae InfectionsSARS-CoV-2Virus ReplicationAntiviral AgentsCarrageenan

Identifiers

PMID33436985
PMCPMC7804421

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.