Evidence map›Paper›PMID 33436818›Full record

ArticleScientific reports2021

The antimicrobial capacity of Cistus salviifolius and Punica granatum plant extracts against clinical pathogens is related to their polyphenolic composition.

Francisco Javier Álvarez-Martínez, Juan Carlos Rodríguez, Fernando Borrás-Rocher, Enrique Barrajón-Catalán, Vicente Micol

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Anticancer Efficacy and Metabolomic Profiling ofAnti-cancer agents in medicinal chemistry · 2026
    Article
  3. Article
  4. Assessment of the Antimicrobial Activity ofInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Article
  7. Phytochemical Analysis and Therapeutic Potential ofPlants (Basel, Switzerland) · 2025
    Article
  8. Biology, Antioxidant Activity, and Therapeutic Potential ofInternational journal of molecular sciences · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Antibacterial and Antimycotic Activity ofPharmaceuticals (Basel, Switzerland) · 2023
    Review
  16. Urinary Tract Infections Caused by UropathogenicInternational journal of molecular sciences · 2023
    Review
  17. Efficacy of Two MoroccanMolecules (Basel, Switzerland) · 2023
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Francisco Javier Álvarez-MartínezInstituto de Biología Molecular y Celular (IBMC) and Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), Universidad Miguel Hernández (UMH), 03202, Elche, Spain.
Juan Carlos RodríguezMicrobiology Section, University General Hospital of Alicante, Alicante Institute for Health and Biomedical Research (ISABIAL Foundation, Alicante, Spain.
Fernando Borrás-RocherStatistics and Operative Research Department, Miguel Hernández University (UMH), Avda. Universidad s/n, 03202, Elche, Spain.
Enrique Barrajón-CatalánInstituto de Biología Molecular y Celular (IBMC) and Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), Universidad Miguel Hernández (UMH), 03202, Elche, Spain. e.barrajon@umh.es.
Vicente MicolInstituto de Biología Molecular y Celular (IBMC) and Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), Universidad Miguel Hernández (UMH), 03202, Elche, Spain.
Universitat de Miguel Hernández d'Elx · ESCentro de Investigación Biomédica en Red · ESInstituto de investigación sanitaria y biomédica de Alicante

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance poses a serious threat to human health worldwide. Plant compounds may help to overcome antibiotic resistance due to their potential resistance modifying capacity. Several botanical extracts and pure polyphenolic compounds were screened against a panel of eleven bacterial isolates with clinical relevance. The two best performing agents, Cistus salviifolius (CS) and Punica granatum (GP) extracts, were tested against 100 Staphylococcus aureus clinical isolates, which resulted in average MIC

Indexed as

Anti-Bacterial AgentsCistusDrug Resistance, BacterialDrug TaperingPlant ExtractsPolyphenolsPomegranateStaphylococcus aureusAnti-Bacterial AgentsPlant ExtractsPolyphenols

Identifiers

PMID33436818
PMCPMC7803989
OpenAlexW3120312900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.