Evidence map›Paper›PMID 33436777›Full record

ArticleScientific reports2021

Association between endometriosis and risk of systemic lupus erythematosus.

Yu-Hsi Fan, Pui-Ying Leong, Jeng-Yuan Chiou, Yu-Hsun Wang, Ming-Hsiang Ku, James Cheng-Chung Wei

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yu-Hsi FanSchool of Medicine, Chung Shan Medical University, Taichung City, 40201, Taiwan.
Pui-Ying LeongInstitute of Medicine, Chung Shan Medical University, Taichung City, 40201, Taiwan.
Jeng-Yuan ChiouSchool of Health Policy and Management, Chung Shan Medical University, Taichung City, 40201, Taiwan.
Yu-Hsun WangDepartment of Medical Research, Chung Shan Medical University Hospital, Taichung City, 40201, Taiwan.
Ming-Hsiang KuDepartment of Family and Community Medicine, Chung Shan Medical University Hospital, Taichung City, 40201, Taiwan.
James Cheng-Chung WeiInstitute of Medicine, Chung Shan Medical University, Taichung City, 40201, Taiwan. jccwei@gmail.com.
Chung Shan Medical University Hospital · TWChung Shan Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To examine the association between endometriosis and the risk of systemic lupus erythematosus (SLE), this nationwide, population-based, retrospective cohort study was conducted based on National Health Insurance Research Database in Taiwan. Endometriosis (N = 16,758) and non-endometriosis (N = 16,758) groups were identified by matching baseline characteristics and comorbidities. Student's t-tests and the Kaplan-Meier estimator were utilized to estimate the hazard ratio (HR) and cumulative probability of SLE in the two groups. The endometriosis group showed a significantly higher incidence density rate (0.3 vs. 0.1 per 1000 person-years) and hazard ratio in SLE group (adjusted HR [aHR], 2.37; 95% confidence interval [CI] 1.35-4.14) compared to the non-endometriosis group. Subgroup analysis revealed that patients with endometriosis between 30 and 45 years of age, or were non-steroidal anti-inflammatory drug users, or were hormonal medications-free participants, had higher risks of SLE. For patients with endometriosis, surgical intervention did not significantly impact on the risk of SLE. Our results demonstrated an increased risk of SLE in patients with endometriosis. Clinicians should be aware of this association when managing patients with endometriosis or SLE.

Indexed as

AdultAge FactorsAnti-Inflammatory Agents, Non-SteroidalDatabases, FactualEndometriosisFemaleHumansKaplan-Meier EstimateLupus Erythematosus, SystemicMiddle AgedRetrospective StudiesRiskTaiwanAnti-Inflammatory Agents, Non-Steroidal

Identifiers

PMID33436777
PMCPMC7803765
OpenAlexW3119552048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.