Evidence map›Paper›PMID 33436690›Full record

ArticleScientific reports2021

Synthesis and tumour cell uptake studies of gadolinium(III)-phosphonium complexes.

Andrew J Hall, Amy G Robertson, Leila R Hill, Louis M Rendina

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Easy and versatile preparation ofEJNMMI radiopharmacy and chemistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrew J HallSchool of Chemistry, The University of Sydney, Sydney, NSW, 2006, Australia.
Amy G RobertsonSchool of Chemistry, The University of Sydney, Sydney, NSW, 2006, Australia.
Leila R HillSchool of Chemistry, The University of Sydney, Sydney, NSW, 2006, Australia.
Louis M RendinaSchool of Chemistry, The University of Sydney, Sydney, NSW, 2006, Australia. lou.rendina@sydney.edu.au.
University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synthesis of a new series of Gd(III)-arylphosphonium complexes is described and the solution stability of selected compounds is reported. Their lipophilicity and uptake in human glial (SVG p12) and human glioblastoma multiforme (T98G) cell lines are presented. The in vitro cytotoxicity of all complexes was determined to be low at therapeutically-relevant concentrations. Selected Gd(III) complexes are potential candidates for further investigation as theranostic agents.

Indexed as

Antineoplastic AgentsCell ProliferationGadoliniumGlioblastomaHumansOrganophosphorus CompoundsTissue DistributionTumor Cells, CulturedAntineoplastic AgentsGadoliniumOrganophosphorus Compounds

Identifiers

PMID33436690
PMCPMC7804430
OpenAlexW3121126893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.