Evidence map›Paper›PMID 33436508›Full record

ArticlemSystems2021

Transcription Inhibitors with XRE DNA-Binding and Cupin Signal-Sensing Domains Drive Metabolic Diversification in

Julian Trouillon, Michel Ragno, Victor Simon, Ina Attrée, Sylvie Elsen

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 38 citations in OpenAlex.

  1. An XRE-type regulator inMicrobiology spectrum · 2026
    Article
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  6. The XRE family protein DbuR is a transcriptional repressor of theApplied and environmental microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Julian TrouillonUniversité Grenoble Alpes, Bacterial Pathogenesis and Cellular Responses team, CNRS ERL5261, CEA IRIG-BCI, INSERM UMR1036, Grenoble, France julian.trouillon@gmail.com sylvie.elsen@cea.fr.ORCID https://orcid.org/0000-0003-1675-0896
Michel RagnoUniversité Grenoble Alpes, Bacterial Pathogenesis and Cellular Responses team, CNRS ERL5261, CEA IRIG-BCI, INSERM UMR1036, Grenoble, France.
Victor SimonUniversité Grenoble Alpes, Bacterial Pathogenesis and Cellular Responses team, CNRS ERL5261, CEA IRIG-BCI, INSERM UMR1036, Grenoble, France.
Ina AttréeUniversité Grenoble Alpes, Bacterial Pathogenesis and Cellular Responses team, CNRS ERL5261, CEA IRIG-BCI, INSERM UMR1036, Grenoble, France.ORCID https://orcid.org/0000-0002-2580-764X
Sylvie ElsenUniversité Grenoble Alpes, Bacterial Pathogenesis and Cellular Responses team, CNRS ERL5261, CEA IRIG-BCI, INSERM UMR1036, Grenoble, France julian.trouillon@gmail.com sylvie.elsen@cea.fr.ORCID https://orcid.org/0000-0003-4611-4719
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcription factors (TFs) are instrumental in the bacterial response to new environmental conditions. They can act as direct signal sensors and subsequently induce changes in gene expression leading to physiological adaptation. Here, by combining transcriptome sequencing (RNA-seq) and cistrome determination (DAP-seq), we studied a family of eight TFs in

Indexed as

DAP-seqglobal regulatory networksPseudomonas aeruginosaRNA-seqtranscription factorsXRE-cupin

Identifiers

PMID33436508
PMCPMC7901475
OpenAlexW3120398872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.