Evidence map›Paper›PMID 33436441›Full record

ArticlemBio2021

Puf4 Mediates Post-transcriptional Regulation of Cell Wall Biosynthesis and Caspofungin Resistance in Cryptococcus neoformans.

Murat C Kalem, Harini Subbiah, Jay Leipheimer, Virginia E Glazier, John C Panepinto

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 40 citations in OpenAlex.

  1. Nanobody-based analysis of RhoGTPase stress response inBiotechnology reports (Amsterdam, Netherlands) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Genomic Characterization ofVeterinary sciences · 2025
    Article
  8. Article
  9. Expression of 1,3-β-glucan synthase subunits inAntimicrobial agents and chemotherapy · 2025
    Article
  10. Puf4 -mediated oxidative stress virulence attenuation inFrontiers in cellular and infection microbiology · 2025
    Article
  11. A fungal protein organizes both glycogen and cell wall glucans.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. The mRNA stability factor Khd4 defines a specific mRNA regulon for membrane trafficking in the pathogenProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Review
  18. Antifungal Effect of Vitamin DJournal of fungi (Basel, Switzerland) · 2023
    Article
  19. Combating increased antifungal drug resistance inActa biochimica et biophysica Sinica · 2023
    Review
  20. Post-transcriptional control of fungal cell wall synthesis.Cell surface (Amsterdam, Netherlands) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Murat C KalemDepartment of Microbiology and Immunology, Witebsky Center for Microbial Pathogenesis and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, Buffalo, New York, USA.ORCID 0000-0003-2415-7435
Harini SubbiahDepartment of Microbiology and Immunology, Witebsky Center for Microbial Pathogenesis and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, Buffalo, New York, USA.
Jay LeipheimerDepartment of Microbiology and Immunology, Witebsky Center for Microbial Pathogenesis and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, Buffalo, New York, USA.
Virginia E GlazierDepartment of Biology, Niagara University, Niagara, New York, USA.
John C PanepintoDepartment of Microbiology and Immunology, Witebsky Center for Microbial Pathogenesis and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, Buffalo, New York, USA jcp25@buffalo.edu.ORCID 0000-0002-1162-0403
University at Buffalo, State University of New York · USNiagara University · US

Funding

Supplement to: Stress Responsive Reprogramming of Translating mRNA Pools in C. neoformansR01AI131977 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI John C Panepinto · 2017 to 2026
$3.6M
Regulation of Intrinsic Caspofungin Resistance in C. neoformansR21AI133133 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI PANEPINTO, JOHN C · 2018 to 2019
$412k
NIAID NIH HHS R01 AI131977NIAID NIH HHS R21 AI133133
6 · The paper itself

Abstract

The human fungal pathogen

Indexed as

Antifungal Agentsbeta-GlucansCaspofunginCell WallChitinChitin SynthaseCryptococcosisCryptococcus neoformansDrug Resistance, FungalEchinocandinsFungal ProteinsGlucansGlucosyltransferasesHumansMembrane ProteinsRNA-Binding ProteinsAntifungal Agentsbeta-1,3-glucanbeta-GlucansCaspofunginChitinChitin SynthaseEchinocandinsFKS1 protein, S cerevisiaeFungal ProteinsGlucansglucan synthaseGlucosyltransferasesMembrane ProteinsRNA-Binding ProteinsSaccharomyces cerevisiae Proteinsantifungal resistancecaspofungincell wallpost-transcriptionalRNA-binding proteins

Identifiers

PMID33436441
PMCPMC7844544
OpenAlexW3119705313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.