ArticleBMJ open respiratory research2021
Sleep apnoea is a risk factor for severe COVID-19.
Article in BMJ open respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.
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Who cites it
69 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.
- Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Pre-diagnosed sleep apnoea is linked to severe courses in community-acquired pneumonia.ERJ open research · 2026Article
- Obstructive sleep apnea, positive airway pressure therapy, and COVID-19 outcomes.Sleep & breathing = Schlaf & Atmung · 2026Article
- Factors affecting COVID-19 outcomes in Ireland: findings from a national database of 1,408,249 cases diagnosed between 2020 and 2022.BMC public health · 2025Article
- Association between obstructive sleep apnea (OSA) and COVID-19 severity.Journal of sleep research · 2025Article
- Lifestyle change during the COVID-19 pandemic in Japan: implications for continuous positive airway pressure adherence in obstructive sleep apnea patient.Journal of thoracic disease · 2025Article
- Neuropsychiatric Manifestations of Long COVID-19: A Narrative Review of Clinical Aspects and Therapeutic Approaches.Life (Basel, Switzerland) · 2025Review
- Incident obstructive sleep apnea in patients with primary aldosteronism following COVID-19 infection: a health global federated network analysis.Therapeutic advances in chronic disease · 2025Article
- Evaluating the Severity of COVID-19 Infection in Patients With Obstructive Sleep Apnea in Jordan.Pulmonary medicine · 2025Article
- Article
- Surgical removal of tonsils and risk of COVID-19: a nested case-control study using data from UK Biobank and AMORIS Cohort.BMC medicine · 2024Article
- Obstructive Sleep Apnea and Acute Lower Respiratory Tract Infections: A Narrative Literature Review.Antibiotics (Basel, Switzerland) · 2024Review
- Genetic Analysis of Obstructive Sleep Apnea and Its Relationship with Severe COVID-19.Annals of the American Thoracic Society · 2024Article
- Snoring-generated fluid droplets as a potential mechanistic link between sleep-disordered breathing and pneumonia.Respiratory research · 2024Article
- Identification of biomarkers and pathways for the SARS-CoV-2 infections in obstructive sleep apnea patients based on machine learning and proteomic analysis.BMC pulmonary medicine · 2024Article
- Association between undiagnosed obstructive sleep apnea and severe course of COVID-19: a prospective observational study.Sleep & breathing = Schlaf & Atmung · 2024Observational
- Association between risk of obstructive sleep apnea severity and risk of severe COVID-19 symptoms: insights from salivary and serum cytokines.Frontiers in public health · 2024Article
- Article
- Implementing a Multidisciplinary Post-COVID Clinic in a Small Community Environment.Archives of rehabilitation research and clinical translation · 2023Article
- Insomnia, Poor Sleep Quality and Sleep Duration, and Risk for COVID-19 Infection and Hospitalization.The American journal of medicine · 2023Article
9 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObstructive sleep apnoea (OSA) is associated with higher body mass index (BMI), diabetes, older age and male gender, which are all risk factors for severe COVID-19.We aimed to study if OSA is an independent risk factor for COVID-19 infection or for severe COVID-19.
methodsOSA diagnosis and COVID-19 infection were extracted from the hospital discharge, causes of death and infectious diseases registries in individuals who participated in the FinnGen study (n=260 405). Severe COVID-19 was defined as COVID-19 requiring hospitalisation. Multivariate logistic regression model was used to examine association. Comorbidities for either COVID-19 or OSA were selected as covariates. We performed a meta-analysis with previous studies.
resultsWe identified 445 individuals with COVID-19, and 38 (8.5%) of them with OSA of whom 19 out of 91 (20.9%) were hospitalised. OSA associated with COVID-19 hospitalisation independent from age, sex, BMI and comorbidities (p-unadjusted=5.13×10
conclusionRisk for contracting COVID-19 was the same for patients with OSA and those without OSA. In contrast, among COVID-19 positive patients, OSA was associated with higher risk for hospitalisation. Our findings are in line with earlier works and suggest OSA as an independent risk factor for severe COVID-19.
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