Evidence map›Paper›PMID 33436107›Full record

ArticleEpidemiology and infection2020

Temperature and humidity associated with increases in tuberculosis notifications: a time-series study in Hong Kong.

M Xu, Y Li, B Liu, R Chen, L Sheng, S Yan, H Chen, J Hou, L Yuan, L Ke and 2 more

Open access · goldAbstract read
In one paragraph

Article in Epidemiology and infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Impact of indoor ventilation on TB transmission risk: implications of climate change.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

M XuKey Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan430030, Hubei, China.
Y LiDepartment of Tuberculosis Prevention, Wuhan Pulmonary Hospital, Wuhan430030, Hubei, China.
B LiuCentre of Health Administration and Development Studies, Hubei University of Medicine, Shiyan442000, Hubei, China.
R ChenFaculty of Education, Health and Wellbeing, University of Wolverhampton, Wolverhampton, UK.
L ShengDepartment of Stomatology, Affiliated People's Hospital of Hubei Medical College, Shiyan442000, Hubei, China.
S YanDepartment of Epidemiology and Biostatistics and State Key Laboratory of Environment Health, Huazhong University of Science and Technology, Wuhan430030, Hubei, China.
H ChenBiological Products Management Office, Hubei Provincial Centre for Disease Control and Prevention, Wuhan, Hubei, China.
J HouDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou450052, Henan, China.
L YuanShanghai University of Medicine & Health Sciences, Affiliated Sixth People's Hospital South Campus, Shanghai201499, China.
L KeCentre of Health Administration and Development Studies, Hubei University of Medicine, Shiyan442000, Hubei, China.
M FanKey Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan430030, Hubei, China.
P HuKey Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan430030, Hubei, China.ORCID 0000-0001-5835-909X
Hubei University of Medicine · CNMinistry of Ecology and Environment · CNHuazhong Agricultural University · CNHubei Provincial Center for Disease Control and Prevention · CNShanghai University of Medicine and Health Sciences · CNUniversity of Wolverhampton · GBWuhan Pulmonary Hospital · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have revealed associations of meteorological factors with tuberculosis (TB) cases. However, few studies have examined their lag effects on TB cases. This study was aimed to analyse nonlinear lag effects of meteorological factors on the number of TB notifications in Hong Kong. Using a 22-year consecutive surveillance data in Hong Kong, we examined the association of monthly average temperature and relative humidity with temporal dynamics of the monthly number of TB notifications using a distributed lag nonlinear models combined with a Poisson regression. The relative risks (RRs) of TB notifications were >1.15 as monthly average temperatures were between 16.3 and 17.3 °C at lagged 13-15 months, reaching the peak risk of 1.18 (95% confidence interval (CI) 1.02-1.35) when it was 16.8 °C at lagged 14 months. The RRs of TB notifications were >1.05 as relative humidities of 60.0-63.6% at lagged 9-11 months expanded to 68.0-71.0% at lagged 12-17 months, reaching the highest risk of 1.06 (95% CI 1.01-1.11) when it was 69.0% at lagged 13 months. The nonlinear and delayed effects of average temperature and relative humidity on TB epidemic were identified, which may provide a practical reference for improving the TB warning system.

Indexed as

HumidityTemperatureAir PollutionHong KongHumansSeasonsTime FactorsTuberculosisRelative humiditytemperaturetuberculosis notification

Identifiers

PMID33436107
PMCPMC8057503
OpenAlexW3115750108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.