ArticleSystematic reviews2021
Screening for depression in children and adolescents: a protocol for a systematic review update.
Article in Systematic reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- AI-enabled and comparator digital interventions for adolescent mental health (2020-2025): early detection, human-AI collaboration, and ethical governance-a PRISMA-ScR scoping review.Frontiers in child and adolescent psychiatry · 2026Pooled it
- Screening for depression in children and adolescents in primary care or non-mental health settings: a systematic review update.Systematic reviews · 2024Pooled it
- Meta-analysis of the relationship between bullying and depressive symptoms in children and adolescents.BMC psychiatry · 2023Pooled it
- The effect of stressful life events on adolescents with depression: the chain mediating role of basic psychological needs and self-esteem.BMC psychology · 2026Article
- Pharmacovigilance of SSRIs in Children and Adolescents with Depression: Disproportionality Analysis of Serotonin Adverse Events Using the FAERS Database.Current medicinal chemistry · 2026Article
- Assessing large language model responses to pediatric depression FAQs: a cross-sectional study on readability, accuracy, and sentiment.Frontiers in psychiatry · 2026Article
- Behavioral and psychological characteristics of adolescents under different Parent-Child relationship patterns: a gender-based perspective.BMC psychology · 2025Article
- Association of Cognitive Function, Quality of Life, and Sleep Disorders in Children With Depression.Actas espanolas de psiquiatria · 2025Article
- Article
- Validation of the Multidimensional Scale of Perceived Social Support (MSPSS) in a Representative Sample of Adolescents: Links with Well-being, Mental Health, and Suicidal Behavior.Psychosocial intervention · 2025Article
- Prevalence of Depressive Disorders in Operatively Treated Pelvic Trauma Patients.Diseases (Basel, Switzerland) · 2025Article
- Validation of the Child Depression Screening Tool in three African settings: Rwanda, Senegal and South Africa.Global mental health (Cambridge, England) · 2025Article
- Trends in Prevalent Cases and Disability-Adjusted Life-Years of Depressive Disorders Worldwide: Findings From the Global Burden of Disease Study From 1990 to 2021.Depression and anxiety · 2025Article
- Impact of expressive suppression on subthreshold depression among college students: a moderated mediation model.Frontiers in psychology · 2025Article
- Information quality of videos related to adolescent depression on social media platforms: a comparative study of TikTok and BiliBili.Frontiers in public health · 2025Article
- Construction of a Nomogram Prediction Model for Individualized Prediction of the Risk of Non Suicidal Self Injury in Adolescent Depression Patients.Neuropsychiatric disease and treatment · 2025Article
- Comparative study on emotional behavior and parental job stress of only-child and non-only-child preschool children.World journal of clinical cases · 2024Article
- Types of diabetes during pregnancy and risk of depression and anxiety in offspring from childhood to young adulthood.Diabetes, obesity & metabolism · 2024Article
- Review
- Diagnosis and management of depression in adolescents.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 12 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMajor depressive disorder is common, debilitating, and affects feelings, thoughts, mood, and behaviors. Childhood and adolescence are critical periods for the development of depression and adolescence is marked by an increased incidence of mental health disorders. This protocol outlines the planned scope and methods for a systematic review update that will evaluate the benefits and harms of screening for depression in children and adolescents.
methodsThis review will update a previously published systematic review by Roseman and colleagues. Eligible studies are randomized controlled trials (RCTs) assessing formal screening in primary care to identify children or adolescents not already self-reporting symptoms of, diagnosed with, or treated for depression. If no or only a single RCT is available, we will consider controlled studies without random assignment. Studies of participants with characteristics associated with an elevated risk of depression will be analyzed separately. Outcomes of interest are symptoms of depression, classification of major depressive disorder based on a validated diagnostic interview, suicidality, health-related quality of life, social function, impact on lifestyle behavior (e.g., substance use, school performance, lost time at work, or school), false-positive results, overdiagnosis, overtreatment, labeling, and other harms such as those arising from treatment. We will search MEDLINE, Embase, PsycINFO, CINAHL, the Cochrane Library, and grey literature sources. Two reviewers will independently screen the titles and abstracts using the liberal accelerated method. Full-text screening will be performed independently by two reviewers using pre-specified eligibility criteria. Data extraction and risk of bias assessments will be performed independently by two reviewers. Pre-planned analyses, including subgroup and sensitivity analyses, are detailed within this protocol. Two independent reviewers will assess and finalize through consensus the certainty of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach, and prepare GRADE evidence profiles and summary of findings tables for each outcome of interest. DISCUSSION: The systematic review will provide a current state of the evidence of benefits and harms of depression screening in children and adolescents. These findings will be used by the Canadian Task Force on Preventive Health Care to inform the development of recommendations on depression screening. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42020150373.
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Registered trials
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