Evidence map›Paper›PMID 33435949›Full record

ArticleBMC pulmonary medicine2021

Pulmonary cavitation: an under-recognized late complication of severe COVID-19 lung disease.

Zaid Zoumot, Maria-Fernanda Bonilla, Ali S Wahla, Irfan Shafiq, Mateen Uzbeck, Rania M El-Lababidi, Fadi Hamed, Mohamed Abuzakouk, Mahmoud ElKaissi

Open access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Air leak with COVID-19 - A meta-summary.Asian cardiovascular & thoracic annals · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Evaluating the Cavitary Lung Lesions on CT Scan of COVID-19 Patients: A Retrospective Study.Journal of community hospital internal medicine perspectives · 2024
    Article
  6. COVID-19 associated lung cavitary lesions: A case series.Caspian journal of internal medicine · 2024
    Article
  7. Article
  8. The impact of COVID-19 on TB in Iran: An illustrative study.Journal of clinical tuberculosis and other mycobacterial diseases · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Haemoptysis in COVID-19 pneumonia.Breathe (Sheffield, England) · 2022
    Article
  17. Article
  18. [Pulmonary cavitations, late complication of COVID-19].Anales del sistema sanitario de Navarra · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zaid ZoumotDepartment of Pulmonology, Respiratory Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates. zzoumot@doctors.org.uk.ORCID http://orcid.org/0000-0003-2533-6160
Maria-Fernanda BonillaDepartment of Infectious Diseases, Medical Specialties Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Ali S WahlaDepartment of Pulmonology, Respiratory Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Irfan ShafiqDepartment of Pulmonology, Respiratory Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Mateen UzbeckDepartment of Pulmonology, Respiratory Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Rania M El-LababidiDepartment of Pharmacy Services, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Fadi HamedCritical Care Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Mohamed AbuzakoukDepartment of Allergy and Immunology, Respiratory Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Mahmoud ElKaissiImaging Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Abu Dhabi Health Services · AEEmirates Foundation · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary radiological findings of the novel coronavirus disease 2019 (COVID-19) have been well documented and range from scattered ground-glass infiltrates in milder cases to confluent ground-glass change, dense consolidation, and crazy paving in the critically ill. However, lung cavitation has not been commonly described in these patients. The objective of this study was to assess the incidence of pulmonary cavitation in patients with COVID-19 and describe its characteristics and evolution.

methodsWe conducted a retrospective review of all patients admitted to our institution with COVID-19 and reviewed electronic medical records and imaging to identify patients who developed pulmonary cavitation.

resultsTwelve out of 689 (1.7%) patients admitted to our institution with COVID-19 developed pulmonary cavitation, comprising 3.3% (n = 12/359) of patients who developed COVID-19 pneumonia, and 11% (n = 12/110) of those admitted to the intensive care unit. We describe the imaging characteristics of the cavitation and present the clinical, pharmacological, laboratory, and microbiological parameters for these patients. In this cohort six patients have died, and six discharged home.

conclusionCavitary lung disease in patients with severe COVID-19 disease is not uncommon, and is associated with a high level of morbidity and mortality.

Indexed as

Tomography, X-Ray ComputedAdultAgedCOVID-19HumansIncidenceLung DiseasesMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexTime FactorsCavityCOVID-19Pulmonary cavitationSARS-CoV-2

Identifiers

PMID33435949
PMCPMC7803002
OpenAlexW3049306217

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.