Evidence map›Paper›PMID 33435741›Full record

Observational studyChronobiology international2021

Rest-activity rhythms in emerging adults: implications for cardiometabolic health.

Elissa K Hoopes, Melissa A Witman, Michele N D'Agata, Felicia R Berube, Benjamin Brewer, Susan K Malone, Michael A Grandner, Freda Patterson

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Chronobiology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Association of physical activity and rest-activity rhythm with sustained attention and melatonin among community-dwelling older adults.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
    Article
  3. Article
  4. Article
  5. Fluctuations in Sleep Duration and Timing and Cardiometabolic Risk.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Age Is Associated With Dampened Circadian Patterns of Rest and Activity: The Study of Muscle, Mobility, and Aging (SOMMA).The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Demographic characteristics associated with circadian rest-activity rhythm patterns: a cross-sectional study.The international journal of behavioral nutrition and physical activity · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Elissa K HoopesCollege of Health Sciences, University of Delaware, Newark, DE, USA.ORCID 0000-0001-6785-7007
Melissa A WitmanCollege of Health Sciences, University of Delaware, Newark, DE, USA.
Michele N D'AgataCollege of Health Sciences, University of Delaware, Newark, DE, USA.
Felicia R BerubeCollege of Health Sciences, University of Delaware, Newark, DE, USA.
Benjamin BrewerCollege of Health Sciences, University of Delaware, Newark, DE, USA.
Susan K MaloneRory Meyers College of Nursing, New York University, New York, NY, USA.
Michael A GrandnerCollege of Medicine, University of Arizona at Tucson, Tucson, AZ, USA.
Freda PattersonCollege of Health Sciences, University of Delaware, Newark, DE, USA.
University of Delaware · USNew York University · USUniversity of Arizona · US

Funding

Vascular Consequences of Duchenne Muscular DystrophyP20GM113125 · NIGMS · UNIVERSITY OF DELAWARE · PI LENNON, SHANNON L. · 2016 to 2025
$23.3M
Using Sleep Health to Optimize Smoking Cessation Treatment Response in HIV-Positive AdultsR01DA051321 · NIDA · UNIVERSITY OF ARIZONA · PI FANTRY, LORI E, GRANDNER, MICHAEL A · 2020 to 2024
$4.1M
Predicting Sleep, Smoking and Lung Health Disparities in at-risk Black African American AdultsR01MD012734 · NIMHD · TEMPLE UNIV OF THE COMMONWEALTH · PI PATTERSON, FREDA, SATTI, ADITI GHATGE · 2018 to 2022
$3.2M
NIDA NIH HHS R01 DA051321NIGMS NIH HHS P20 GM113125NIMHD NIH HHS R01 MD012734
6 · The paper itself

Abstract

Emerging adulthood (18-25 years) represents a window of opportunity to modify the trajectory of cardiometabolic disease risk into older adulthood. Not known is the extent to which rest-activity rhythms (RAR) may be related to biomarkers of cardiometabolic health in this population. In this cross-sectional, observational study, 52 healthy emerging adults wore wrist accelerometers (14 consecutive days; 24 h/day) for assessment of nonparametric RAR metrics, including interdaily stability (IS; day-to-day RAR consistency), intradaily variability (IV; within-day RAR fragmentation), and relative amplitude (RA; robustness of RAR), as well as autocorrelation (correlation of rest/activity levels at 24-h lag-times). Cardiometabolic biomarkers, including body mass index (BMI), body fat percentage, blood pressure (BP), fasting lipids, glucose, and C-reactive protein (CRP) were assessed. Additional measures including physical activity, sleep duration, and habitual caffeine and alcohol consumption were also evaluated. A series of multivariable regression models of cardiometabolic biomarkers were used to quantify associations with RAR metrics. On average, participants were 20 ± 1 years of age (21 males, 31 females), non-obese, and non-hypertensive. All were nonsmokers and free of major diseases or conditions. In separate models, which adjusted for sex, BMI, moderate-vigorous physical activity, sleep duration, caffeine, and alcohol consumption, IS was inversely associated with total cholesterol (p ≤ 0.01) and non-HDL cholesterol (

Indexed as

Cardiovascular DiseasesSleepAdultAgedBody Mass IndexCircadian RhythmCross-Sectional StudiesFemaleHumansMaleRestactigraphybody activity 24-h rhythmcardiometabolic riskEmerging adultsinterdaily stabilityintradaily variabilityrelative amplitude

Identifiers

PMID33435741
PMCPMC8035288
OpenAlexW3119854886

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.