Evidence map›Paper›PMID 33435575›Full record

ArticlePathogens (Basel, Switzerland)2021

Engineered Phage Endolysin Eliminates

Christine Landlinger, Lenka Tisakova, Vera Oberbauer, Timo Schwebs, Abbas Muhammad, Agnieszka Latka, Leen Van Simaey, Mario Vaneechoutte, Alexander Guschin, Gregory Resch and 3 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 2 pooled it
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.

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  15. Bacteriophage-mediated reduction of uropathogenicbioRxiv : the preprint server for biology · 2025
    Article
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  20. [Phage endolysins-a novel class of antibacterial agents with a wide range of applications].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 6 countries.

Christine LandlingerPhagoMed Biopharma GmbH, Vienna Biocenter, 1110 Wien, Austria.
Lenka TisakovaPhagoMed Biopharma GmbH, Vienna Biocenter, 1110 Wien, Austria.ORCID 0000-0002-2891-0888
Vera OberbauerPhagoMed Biopharma GmbH, Vienna Biocenter, 1110 Wien, Austria.ORCID 0000-0001-9111-4625
Timo SchwebsPhagoMed Biopharma GmbH, Vienna Biocenter, 1110 Wien, Austria.
Abbas MuhammadPhagoMed Biopharma GmbH, Vienna Biocenter, 1110 Wien, Austria.
Agnieszka LatkaLaboratory Bacteriology Research, Department of Diagnostic Sciences, Faculty of Medicine & Health Sciences, Ghent University, Flanders, 9000 Gent, Belgium.
Leen Van SimaeyLaboratory Bacteriology Research, Department of Diagnostic Sciences, Faculty of Medicine & Health Sciences, Ghent University, Flanders, 9000 Gent, Belgium.
Mario VaneechoutteLaboratory Bacteriology Research, Department of Diagnostic Sciences, Faculty of Medicine & Health Sciences, Ghent University, Flanders, 9000 Gent, Belgium.ORCID 0000-0002-4586-203X
Alexander GuschinMoscow Scientific and Practical Center of Dermatovenerology and Cosmetology Moscow, 119071 Moscow, Russia.ORCID 0000-0002-0399-1167
Gregory ReschDepartment of Fundamental Microbiology, University of Lausanne, 1015 Lausanne, Switzerland.ORCID 0000-0003-2341-4591
Sonja SwidsinskiMDI Limbach Berlin GmbH, 13407 Berlin, Germany.
Alexander SwidsinskiMedizinische Klinik, Charité CCM, Humboldt Universität, 10117 Berlin, Germany.
Lorenzo CorsiniPhagoMed Biopharma GmbH, Vienna Biocenter, 1110 Wien, Austria.
Vienna Biocenter · ATGhent University · BESechenov University · RUSiemens Healthineers (Germany) · DEState Research Center for Dermatovenereology and Cosmetology · RUUniversity of Lausanne · CHUniversity of Wrocław · PL

Funding

Österreichische Forschungsförderungsgesellschaft 876839
6 · The paper itself

Abstract

Bacterial vaginosis is characterized by an imbalance of the vaginal microbiome and a characteristic biofilm formed on the vaginal epithelium, which is initiated and dominated by

Indexed as

alternative to antibiotic treatmentantimicrobial resistancebacterial vaginosisendolysinGardnerella biofilmgenus-specificityprophage

Identifiers

PMID33435575
PMCPMC7830407
OpenAlexW3120586285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.