Evidence map›Paper›PMID 33435209›Full record

ArticleAnimals : an open access journal from MDPI2021

Dietary l-carnitine Supplementation Modifies the Lipopolysaccharide-Induced Acute Phase Reaction in Dairy Cows.

Jennifer Meyer, Susanne Ursula Kononov, Sandra Grindler, Johanna Tröscher-Mußotter, Mohamad Taher Alaedin, Jana Frahm, Liane Hüther, Jeannette Kluess, Susanne Kersten, Dirk von Soosten and 9 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 1 country.

Jennifer MeyerInstitute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.
Susanne Ursula KononovInstitute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.
Sandra GrindlerInstitute of Animal Science, Functional Anatomy of Livestock, University of Hohenheim, Fruwirthstraße 35, 70593 Stuttgart, Germany.
Johanna Tröscher-MußotterInstitute of Animal Science, Functional Microbiology of Livestock, University of Hohenheim, Emil-Wolff-Str. 8, 70593 Stuttgart, Germany.
Mohamad Taher AlaedinInstitute for Animal Science, Physiology and Hygiene, Rheinische Friedrich-Wilhelms-Universität Bonn, Katzenburgweg 7-9, 53115 Bonn, Germany.
Jana FrahmInstitute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.ORCID 0000-0003-1770-5229
Liane HütherInstitute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.
Jeannette KluessInstitute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.
Susanne KerstenInstitute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.ORCID 0000-0003-2032-4267
Dirk von SoostenInstitute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.ORCID 0000-0003-3425-5055
Ulrich MeyerInstitute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.
Erika MostInstitute of Animal Nutrition and Nutrition Physiology, Justus-Liebig-Universität Gießen, Heinrich-Buff-Ring 26-32, 35392 Gießen, Germany.
Klaus EderInstitute of Animal Nutrition and Nutrition Physiology, Justus-Liebig-Universität Gießen, Heinrich-Buff-Ring 26-32, 35392 Gießen, Germany.ORCID 0000-0003-3246-4136
Helga SauerweinInstitute for Animal Science, Physiology and Hygiene, Rheinische Friedrich-Wilhelms-Universität Bonn, Katzenburgweg 7-9, 53115 Bonn, Germany.ORCID 0000-0002-6905-4053
Jana SeifertInstitute of Animal Science, Functional Microbiology of Livestock, University of Hohenheim, Emil-Wolff-Str. 8, 70593 Stuttgart, Germany.ORCID 0000-0002-7690-8539
Korinna HuberInstitute of Animal Science, Functional Anatomy of Livestock, University of Hohenheim, Fruwirthstraße 35, 70593 Stuttgart, Germany.
Anja WegerichClinic for Cattle, University of Veterinary Medicine Hannover, Foundation, Bischofsholer Damm 15, 30173 Hannover, Germany.ORCID 0000-0003-4057-9275
Jürgen RehageClinic for Cattle, University of Veterinary Medicine Hannover, Foundation, Bischofsholer Damm 15, 30173 Hannover, Germany.ORCID 0000-0001-8007-1834
Sven DänickeInstitute of Animal Nutrition, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Bundesallee 37, 38116 Braunschweig, Germany.ORCID 0000-0002-4913-4726
Friedrich-Loeffler-Institut · DEUniversity of Hohenheim · DEJustus-Liebig-Universität Gießen · DEUniversity of Bonn · DEUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

Deutsche Forschungsgemeinschaft 202989534
6 · The paper itself

Abstract

l-carnitine plays an important role in energy metabolism through supporting the transport of activated fatty acids to the subcellular site of β-oxidation. An acute phase reaction (APR) is known as an energy consuming process. Lipopolysaccharides (LPS) are often used in animal models to study intervention measures during innate immune responses such as APR. Thus, the aim of the study was to investigate the effects of dietary l-carnitine supplementation during an LPS-induced APR in mid-lactating German Holstein cows. Animals were assigned to a control (CON, n = 26) or l-carnitine group (CAR,

Indexed as

clinical scoredairy cowenergy metabolisminsulinl-carnitinelipopolysaccharidenon-esterified fatty acidsperformancesystemic inflammation

Identifiers

PMID33435209
PMCPMC7828073
OpenAlexW3118310848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.