Evidence map›Paper›PMID 33435208›Full record

ArticleInternational journal of molecular sciences2021

Molecular and Structural Evolution of Cytochrome P450 Aromatase.

Giovanna Di Nardo, Chao Zhang, Anna Giulia Marcelli, Gianfranco Gilardi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 35 citations in OpenAlex.

  1. The Papilla Stage as a Critical Molecular Transition:Animals : an open access journal from MDPI · 2026
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  13. A Review onGenes · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Giovanna Di NardoDepartment of Life Sciences and Systems Biology, University of Torino, via Accademia Albertina 13, 1023 Torino, Italy.ORCID 0000-0002-4169-2635
Chao ZhangDepartment of Life Sciences and Systems Biology, University of Torino, via Accademia Albertina 13, 1023 Torino, Italy.
Anna Giulia MarcelliDepartment of Life Sciences and Systems Biology, University of Torino, via Accademia Albertina 13, 1023 Torino, Italy.ORCID 0000-0001-6563-8150
Gianfranco GilardiDepartment of Life Sciences and Systems Biology, University of Torino, via Accademia Albertina 13, 1023 Torino, Italy.ORCID 0000-0002-6559-276X
Accademia Albertina delle Belle Arti · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aromatase is the cytochrome P450 enzyme converting androgens into estrogen in the last phase of steroidogenesis. As estrogens are crucial in reproductive biology, aromatase is found in vertebrates and the invertebrates of the genus

Indexed as

Evolution, MolecularAmino Acid SequenceAnimalsAromataseCatalytic DomainEstrogensHumansModels, MolecularSequence AlignmentStructure-Activity RelationshipVertebratesAromataseCYP19A1 protein, humanEstrogensaromataseconservationcytochrome P450estrogensmolecular evolutionstructural alignmentsubstrate recognition sites

Identifiers

PMID33435208
PMCPMC7827799
OpenAlexW3118620135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.