ReviewJournal of clinical medicine2021
The Human Cutaneous Sensory Corpuscles: An Update.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.
- The Lamellar Cells of Vertebrate Meissner and Pacinian Corpuscles: Development, Characterization, and Functions.Frontiers in neuroscience · 2022Pooled it
- Exploratory Immunohistochemical Mapping of Mechanosensitivity-Associated Ion Channel Proteins in Terminal Glial Cells of Human Meissner and Pacinian Corpuscles.International journal of molecular sciences · 2026Article
- Bioinspired High-Resolution, Wide-Range Pressure Sensor Enabled by Synergistic CB/CNT Island-Chain and PVDF/PDMS Fiber Network for Dexterous Robotic Hands.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- In Vitro Antifungal and Wound-Healing Potential ofAntibiotics (Basel, Switzerland) · 2026Article
- Trapezius fascia reveals mechanosensory capacity and predominance of nociceptive axons in occipital neuralgia.Scientific reports · 2026Article
- The sensory penis: A comprehensive immunohistological and ontogenetic exploration of human penile innervation.Andrology · 2026Article
- From the TPR pathway and the neuroimmune unit to the cutaneous HPA axis: a neuro-endo-immune cross-talk in rosacea.Frontiers in medicine · 2026Review
- Detection of neuron specific enolase in the lip and ear pinna of goat (Capra hircus): an immunohistochemical study.BMC veterinary research · 2025Article
- Autoantibodies against Components of Sensory Nerve Formations in the Intervertebral Disks and Adjacent Structures are Antigens Recognized by the Sera from Patients Affected by a New Variant of Endemic Pemphigus in El Bagre, Colombia.Dermatology practical & conceptual · 2025Article
- The Role of Natural Hydrogels in Enhancing Wound Healing: From Biomaterials to Bioactive Therapies.Pharmaceutics · 2025Review
- In situ electric field dosimetry analysis for powerline frequency peripheral nerve magnetic stimulation.Scientific reports · 2025Article
- Sexual Mechanosensitivity: Age-Related Changes in the Innervation of the Human Prepuce.Journal of clinical medicine · 2025Article
- Bio-inspired artificial mechanoreceptors with built-in synaptic functions for intelligent tactile skin.Nature materials · 2025Article
- Ultrasonographic Identification of Pacinian Corpuscles in the Hand: A Pilot Study of Technique and Reliability.Muscle & nerve · 2025Article
- Immunohistochemical Detection of Tentonin-3/TMEM150C in Human Dorsal Root Ganglion, Cutaneous End-Organ Complexes, and Muscle Spindles.Brain sciences · 2025Article
- The role of skin hydration, skin deformability, and age in tactile friction and perception of materials.Scientific reports · 2025Article
- The inner core enables transient touch detection in the Pacinian corpuscle.Science advances · 2025Article
- Periarticular Proprioception: Analyzing the Three-Dimensional Structure of Corpuscular Mechanosensors in the Dorsal Part of the Scapholunate Ligament.Cells, tissues, organs · 2025Article
- Comparative study on the distribution of Pacinian corpuscles in the pancreas.Frontiers in neuroanatomy · 2025Article
- Different Correlation Patterns Between Circulating Amino Acids and Body Temperature in Fibromyalgia Syndrome: A Cross-Sectional Study.International journal of molecular sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sensory corpuscles of human skin are terminals of primary mechanoreceptive neurons associated with non-neuronal cells that function as low-threshold mechanoreceptors. Structurally, they consist of an extreme tip of a mechanosensory axon and nonmyelinating peripheral glial cells variably arranged according to the morphotype of the sensory corpuscle, all covered for connective cells of endoneurial and/or perineurial origin. Although the pathologies of sensitive corpuscles are scarce and almost never severe, adequate knowledge of the structure and immunohistochemical profile of these formations is essential for dermatologists and pathologists. In fact, since sensory corpuscles and nerves share a basic structure and protein composition, a cutaneous biopsy may be a complementary method for the analysis of nerve involvement in peripheral neuropathies, systemic diseases, and several pathologies of the central nervous system. Thus, a biopsy of cutaneous sensory corpuscles can provide information for the diagnosis, evolution, and effectiveness of treatments of some pathologies in which they are involved. Here, we updated and summarized the current knowledge about the immunohistochemistry of human sensory corpuscles with the aim to provide information to dermatologists and skin pathologists.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.