Evidence map›Paper›PMID 33434499›Full record

ReviewChest2021

Protein Biomarkers for COPD Outcomes.

Karina A Serban, Katherine A Pratte, Russell P Bowler

Open access · greenAbstract readReview
In one paragraph

Review in Chest, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 92 citations in OpenAlex.

  1. Article
  2. Article
  3. Circulating proteomic landscape of lung function.The European respiratory journal · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Dynamic and prognostic proteomic associations with FEVmedRxiv : the preprint server for health sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Karina A SerbanNational Jewish Health, Denver; University of Colorado, Anschutz Medical Campus, Aurora, CO. Electronic address: serbank@njhealth.org.
Katherine A PratteNational Jewish Health, Denver.
Russell P BowlerNational Jewish Health, Denver; University of Colorado, Anschutz Medical Campus, Aurora, CO.
University of Colorado Denver · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Biomarker of Lung Disease in African AmericansR01HL137995 · NHLBI · NATIONAL JEWISH HEALTH · PI BOWLER, RUSSELL PAUL, KECHRIS-MAYS, KATHERINA · 2018 to 2021
$3.4M
Multi-omic networks associated with COPD progression in TOPMed CohortsR01HL152735 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI BANAEI-KASHANI, FARNOUSH, BOWLER, RUSSELL PAUL · 2020 to 2023
$3.1M
Mannose binding lectin-dependent complement activation in emphysemaK08HL141770 · NHLBI · NATIONAL JEWISH HEALTH · PI SERBAN, KARINA · 2019 to 2023
$793k
NHLBI NIH HHS K08 HL141770NHLBI NIH HHS R01 HL137995NHLBI NIH HHS R01 HL152735
6 · The paper itself

Abstract

COPD is a clinically heterogeneous syndrome characterized by injury to airways, airspaces, and lung vasculature and usually caused by tobacco smoke and/or air pollution exposure. COPD is also independently associated with nonpulmonary comorbidities (eg, cardiovascular disease) and malignancies (eg, GI, bladder), suggesting a role for systemic injury. Since not all those with exposure develop COPD, there has been a search for plasma and lung biomarkers that confer increased cross-sectional and longitudinal risk. This search typically focuses on clinically relevant COPD outcomes such as FEV

Indexed as

ProteomicsBlood ProteinsHumansPrognosisPulmonary Disease, Chronic ObstructiveBlood Proteinsbiomarker networkCOPDmultiplex platformsprotein biomarker

Identifiers

PMID33434499
PMCPMC8213963
OpenAlexW3118838717

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.