Evidence map›Paper›PMID 33434482›Full record

ArticleCurrent biology : CB2021

Hypoxia: Uncharged tRNA to the Rescue!

Thomas E Mulroney, Tuija Pöyry, Anne E Willis

Abstract readEditorialComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Thomas E MulroneyMRC Toxicology Unit, University of Cambridge, Tennis Court Rd, Cambridge CB2 1QW, UK. Electronic address: tem37@cam.ac.uk.
Tuija PöyryMRC Toxicology Unit, University of Cambridge, Tennis Court Rd, Cambridge CB2 1QW, UK.
Anne E WillisMRC Toxicology Unit, University of Cambridge, Tennis Court Rd, Cambridge CB2 1QW, UK. Electronic address: aew80@cam.ac.uk.

Funding

Medical Research Council MC_UP_A600_1023Medical Research Council MC_UU_00025/7
6 · The paper itself

Abstract

A new study has identified genes that protect Caenorhabditis elegans from hypoxic stress. Genomic approaches and whole-organism proteomics reveal a regulatory interaction between a threonyl-tRNA synthetase and ribosome biogenesis that modulates global translation and hypoxic sensitivity.

Indexed as

Amino Acyl-tRNA SynthetasesThreonine-tRNA LigaseAnimalsCaenorhabditis elegansHypoxiaRNA, TransferAmino Acyl-tRNA SynthetasesRNA, TransferThreonine-tRNA Ligase

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.