ArticlePloS one2021
Detection of postural control in early Parkinson's disease: Clinical testing vs. modulation of center of pressure.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Instrumental balance assessment in Parkinson's disease and parkinsonism. A systematic review with critical appraisal of clinical applications and quality of reporting.Frontiers in neurology · 2025Pooled it
- Frequency-based deep learning to identify subtle postural instability in early, untreated Parkinson's disease.NPJ Parkinson's disease · 2026Article
- When the body resonates with the pain of the other: Empathy Bodyssence in Parkinson's disease.Neuroscience of consciousness · 2026Article
- Characteristics of Postural Instability in Idiopathic Normal Pressure Hydrocephalus.Neurology and therapy · 2025Article
- Multi-Domain CoP Feature Analysis of Functional Mobility for Parkinson's Disease Detection Using Wearable Pressure Insoles.Sensors (Basel, Switzerland) · 2025Article
- Stability vs. performance: The role of weight shift during gait initiation for people with Parkinson disease.Journal of biomechanics · 2025Article
- A Refined Vestibular Romberg Test to Differentiate Somatosensory from Vestibular-Induced Disequilibrium.Diagnostics (Basel, Switzerland) · 2025Article
- Sway frequencies may predict postural instability in Parkinson's disease: a novel convolutional neural network approach.Journal of neuroengineering and rehabilitation · 2025Article
- Balance and gait disorders in de novo Parkinson's disease: support for early rehabilitation.Journal of neurology · 2024Article
- Combining Transcranial Direct Current Stimulation with Exercise to Improve Mobility, Stability, and Tremor Management in 25 Individuals with Parkinson's Disease.Neurology international · 2024Article
- Parkinson´s disease cardiovascular symptoms: A new complex functional and structural insight.European journal of neurology · 2024Article
- Kalman filtering to reduce measurement noise of sample entropy: An electroencephalographic study.PloS one · 2024Article
- Changes in postural stability after cerebrospinal fluid tap test in patients with idiopathic normal pressure hydrocephalus.Frontiers in neurology · 2024Article
- The Effect of Skeletal Muscle-Pump on Blood Pressure and Postural Control in Parkinson's Disease.Cardiovascular engineering and technology · 2023Article
- Correlation of balance posturographic parameters during quiet standing with the berg balance scale in patients with parkinson's disease.BMC neurology · 2023Article
- Article
- Trend Change Analysis as a New Tool to Complement the Evaluation of Human Body Balance in the Time and Frequency Domains.Journal of human kinetics · 2023Article
- Article
- Lacunes may worsen cognition but not motor function in Parkinson's disease.Brain and behavior · 2023Article
- The Use of the Static Posturography to Assess Balance Performance in a Parkinson's Disease Population.International journal of environmental research and public health · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLittle is known about the early stage balance changes in PD. Many clinicians assume that there are no postural issues in early PD because of failure to identify them on bedside and clinical testing. Here, we quantify balance changes in early and moderate stage PD and compared these values to healthy controls (HC) using clinical assessments of balance and posturography.
methodsWe compared 15 HC with 15 early PD (PD-II; Hoehn and Yahr stage II) and 15 moderate PD (PD-III; H&Y stage III). Participants performed various clinical tests of balance and a standing postural task on a force platform. We quantified the spatiotemporal parameters of the center of pressure (COP), the sample entropy and power spectral density (PSD) of the COP.
resultsThe PSD of the COP differentiated PD-II from HC from 0-0.5 Hz and PD-II from PD-III from 0.5-1 Hz. Specifically, PD-II and PD-III manifested greater power than HC from 0-0.5 Hz, whereas PD-III exhibited greater power than PD-II and HC from 0.5-1.0 Hz (p<0.05). However, there were no significant differences between PD-II and HC in all clinical tests and in spatiotemporal parameters of the COP (p>0.05). Although the sample entropy was significantly lower in the PD groups (p<0.05), entropy failed to differentiate PD-II from PD-III.
conclusionThe low-frequency modulation of the COP in this small cohort differentiated early PD from HC and from moderate PD. Clinicians should be aware that there are early balance deficits in PD. A larger sample size is needed to confirm these findings.
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