ArticlePloS one2021
Within-session test-retest reliability of pressure pain threshold and mechanical temporal summation in healthy subjects.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Reliability of Temporal Summation of Pain in Healthy and Clinical Populations: A Systematic Review and Meta-Analysis.European journal of pain (London, England) · 2025Pooled it
- Physiological and autonomic responses to intermittent low-lung-volume apnoea and pain sensitivity: A randomized controlled pilot trial.Experimental physiology · 2026Trial
- Immediate clinical and neuromechanical effects of cervical spine manipulation compared to cervical spine mobilization among individuals with chronic neck pain: a randomized mechanistic cross-over trial.Chiropractic & manual therapies · 2026Trial
- Acute effects of aerobic versus combined aerobic and cervical-upper extremity resistance exercise on pressure pain threshold, pain perception, and fatigue in workers exposed to high ergonomic risk with chronic non-specific neck pain: a randomized controlled trial.BMC musculoskeletal disorders · 2026Trial
- Trial
- Effects of 4-Week Treadmill Running at Different Intensities on Exercise-Induced Hypoalgesia and Endogenous Pain Modulation in Healthy Individuals.Pain research & management · 2026Trial
- Exercise induced hypoalgesia during different intensities of a dynamic resistance exercise: A randomized controlled trial.PloS one · 2024Trial
- Expectations affect pain sensitivity changes during massage.The Journal of manual & manipulative therapy · 2023Trial
- Changes in hormones and experimental pain sensitivity in healthy girls: an exploratory longitudinal pilot study.Pain reports · 2026Article
- Validity, Reliability, and Responsiveness of a New Device for Measuring Pressure Pain Thresholds.Journal of clinical medicine · 2026Article
- Blunted exercise-induced hypoalgesia in people with knee pain after a brief low-intensity warm-up: a split-body study with and without blood flow restriction.BMC sports science, medicine & rehabilitation · 2026Article
- Hypoalgesic effects, safety, and feasibility of a 6-minute high-lung-volume static apnea intervention.The Korean journal of pain · 2026Article
- Reliability and standard error of measurement of pressure pain thresholds at articular landmarks.British journal of pain · 2026Article
- Reliability and Validity of Non-Invasive Electrical Detection and Pain Thresholds Using PainVisionJournal of pain research · 2026Article
- Pain modulation profiles in temporomandibular disorders with migraine and fibromyalgia.Journal of oral & facial pain and headache · 2026Article
- High Cardiorespiratory Fitness and Vigorous Physical Activity Relate to Select Pain Sensitivity Assessments in Healthy Adults: A Cross-Sectional Study.Pain research & management · 2026Article
- Evoked temporal summation in dogs to assess pain central sensitization and modulation - A feasibility study.PloS one · 2026Article
- Thermal temporal summation has good reliability in the lumbar region.The Journal of manual & manipulative therapy · 2025Article
- Movement-Evoked Pain and Temporal Summation in Individuals with Symptomatic Rotator Cuff Tears: A Cross-Sectional Study.Life (Basel, Switzerland) · 2025Article
- The Immediate Hypoalgesic Effects of Mobilization and Manipulation in Patients with Non-Specific Chronic Low Back Pain: A Cross-Over Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo determine the absolute and relative intra-rater within-session test-retest reliability of pressure pain threshold (PPT) and mechanical temporal summation of pain (TSP) at the low back and the forearm in healthy participants and to test the influence of the number and sequence of measurements on reliability metrics.
methodsIn 24 participants, three PPT and TSP measures were assessed at four sites (2 at the low back, 2 at the forearm) in two blocks of measurements separated by 20 minutes. The standard error of measurement, the minimal detectable change (MDC) and the intraclass correlation coefficient (ICC) were investigated for five different sequences of measurements (e.g. measurement 1, 1-2, 1-2-3).
resultsThe MDC for the group (MDCgr) for PPT ranged from 28.71 to 50.56 kPa across the sites tested, whereas MDCgr for TSP varied from 0.33 to 0.57 out of 10 (numeric scale). Almost all ICC showed an excellent relative reliability (between 0.80 and 0.97), except when only the first measurement was considered (moderate). Although minimal differences in absolute PPT reliability were present between the different sequences, in general, using only the first measurement increase measurement error. Three TSP measures reduced the measurement error. DISCUSSION: We established that two measurements of PPT and three of TSP reduced the measurement error and demonstrated an excellent relative reliability. Our results could be used in future pain research to confirm the presence of true hypo/hyperalgesia for paradigms such as conditioned pain modulation or exercise-induced hypoalgesia, indicated by a change exceeding the measurement variability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.