Evidence map›Paper›PMID 33434227›Full record

Trial reportPloS one2021

The contributions of focused attention and open monitoring in mindfulness-based cognitive therapy for affective disturbances: A 3-armed randomized dismantling trial.

Brendan Cullen, Kristina Eichel, Jared R Lindahl, Hadley Rahrig, Nisha Kini, Julie Flahive, Willoughby B Britton

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01831362 (Dismantling Mindfulness), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01831362 nacompletednot on this map

Dismantling Mindfulness: Contributions of Attention vs. Acceptance

TypeinterventionalSponsorBrown UniversityRan2013 to 2016Enrolled104ConditionsMild-moderate Unipolar Depression, Persistent Negative AffectArmsMindfulness-Based Cognitive Therapy, Focused Attention (FA), Open- Monitoring
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Systematic Review for the Medical Applications of Meditation in Randomized Controlled Trials.International journal of environmental research and public health · 2022
    Pooled it
  2. Impact of warm mindfulness on emotion regulation: A randomized controlled effectiveness trial.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2023
    Trial
  3. Trial
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Defining and measuring meditation-related adverse effects in mindfulness-based programs.Clinical psychological science : a journal of the Association for Psychological Science · 2021
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Brendan CullenDepartment of Psychiatry and Human Behavior, Brown University Medical School, Providence, RI, United States of America.
Kristina EichelDepartment of Psychiatry and Human Behavior, Brown University Medical School, Providence, RI, United States of America.
Jared R LindahlDepartment of Religious Studies, Brown University, Providence, RI, United States of America.
Hadley RahrigDepartment of Psychiatry and Human Behavior, Brown University Medical School, Providence, RI, United States of America.
Nisha KiniQuantitative Health Sciences Department, University of Massachusetts Medical School, Worcester, MA, United States of America.
Julie FlahiveQuantitative Health Sciences Department, University of Massachusetts Medical School, Worcester, MA, United States of America.
Willoughby B BrittonDepartment of Psychiatry and Human Behavior, Brown University Medical School, Providence, RI, United States of America.ORCID 0000-0002-2983-0863
Brown University · USUniversity of Massachusetts Chan Medical School · US

Funding

Mindfulness Influences on Self-Regulation: Mental and Physical Health ImplicationsUH2AT009145 · NCCIH · BROWN UNIVERSITY · PI BRITTON, WILLOUGHBY, KING, JEAN A · 2015 to 2017
$2.7M
Dismantling Mindfulness: Contributions of Attention vs. AcceptanceK23AT006328 · NCCIH · BROWN UNIVERSITY · PI BRITTON, WILLOUGHBY · 2011 to 2015
$667k
NCCIH NIH HHS K23 AT006328NCCIH NIH HHS UH2 AT009145
6 · The paper itself

Abstract

objectiveMindfulness-based cognitive therapy (MBCT) includes a combination of focused attention (FA) and open monitoring (OM) meditation practices. The aim of this study was to assess both short- and long-term between- and within-group differences in affective disturbance among FA, OM and their combination (MBCT) in the context of a randomized controlled trial.

methodOne hundred and four participants with mild to severe depression and anxiety were randomized into one of three 8-week interventions: MBCT (n = 32), FA (n = 36) and OM (n = 36). Outcome measures included the Inventory of Depressive Symptomatology (IDS), and the Depression Anxiety Stress Scales (DASS). Mixed effects regression models were used to assess differential treatment effects during treatment, post-treatment (8 weeks) and long-term (20 weeks). The Reliable Change Index (RCI) was used to translate statistical findings into clinically meaningful improvements or deteriorations.

resultsAll treatments demonstrated medium to large improvements (ds = 0.42-1.65) for almost all outcomes. While all treatments were largely comparable in their effects at post-treatment (week 8), the treatments showed meaningful differences in rapidity of response and pattern of deteriorations. FA showed the fastest rate of improvement and the fewest deteriorations on stress, anxiety and depression during treatment, but a loss of treatment-related gains and lasting deteriorations in depression at week 20. OM showed the slowest rate of improvement and lost treatment-related gains for anxiety, resulting in higher anxiety in OM at week 20 than MBCT (d = 0.40) and FA (d = 0.36), though these differences did not reach statistical significance after correcting for multiple comparisons (p's = .06). MBCT and OM showed deteriorations in stress, anxiety and depression at multiple timepoints during treatment, with lasting deteriorations in stress and depression. MBCT showed the most favorable pattern for long-term treatment of depression.

conclusionsFA, OM and MBCT show different patterns of response for different dimensions of affective disturbance.

trial registrationThis trial is registered at (v NCT01831362); www.clinicaltrials.gov.

Indexed as

Cognitive Behavioral TherapyAdultAnxiety DisordersDepressive DisorderFemaleHumansMaleMiddle AgedMindfulnessStress, PsychologicalTreatment Outcome

Identifiers

PMID33434227
PMCPMC7802967
OpenAlexW3120547434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.