Evidence map›Paper›PMID 33434083›Full record

ArticleJCO oncology practice2021

Socioeconomic Factors Influence the Impact of Tumor HPV Status on Outcome of Patients With Oropharyngeal Squamous Cell Carcinoma.

Jennifer A Marks, Jeffrey M Switchenko, Conor E Steuer, Martha Ryan, Mihir R Patel, Mark W McDonald, Kristin Higgins, Johnathan J Beitler, Dong M Shin, Theresa W Gillespie and 1 more

Abstract read
In one paragraph

Article in JCO oncology practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Occupational Etiology of Oropharyngeal Cancer: A Literature Review.International journal of environmental research and public health · 2023
    Review
  5. Article
  6. Factors Related to Human Papillomavirus Positivity among Oral Cavity and Pharynx Cancers from Surveillance, Epidemiology and End Results (SEER) Program Data.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jennifer A MarksDepartment of Internal Medicine, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-8592-9892
Jeffrey M SwitchenkoDepartment of Biostatistics & Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA.ORCID 0000-0002-5563-9325
Conor E SteuerDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.
Martha RyanDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.
Mihir R PatelDepartment of Otolaryngology, Emory University School of Medicine, Atlanta, GA.
Mark W McDonaldDepartment of Radiation Oncology, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0003-3021-9356
Kristin HigginsDepartment of Radiation Oncology, Emory University School of Medicine, Atlanta, GA.
Johnathan J BeitlerDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.
Dong M ShinDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-8245-4174
Theresa W GillespieDepartment of Surgery, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0001-8734-716X
Nabil F SabaDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0003-4972-1477

Funding

Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Suresh S Ramalingam · 2009 to 2026
$47.5M
NCI NIH HHS P30 CA138292
6 · The paper itself

Abstract

purposeHuman papilloma virus (HPV) association remains one of the most important predictors of clinical outcome in oropharyngeal squamous cell carcinoma (OPSCC). We aimed to determine whether the relationship between HPV status and overall survival was influenced by socioeconomic factors. MATERIALS AND

methodsUsing the National Cancer Database, we examined the relationship between socioeconomic status and overall survival, controlling for demographics and socioeconomic variables (age at diagnosis, race, sex, clinical stage, facility type, facility location, insurance status, median-income quartiles, percent of no high-school education quartiles, rural-urban dwelling, Charlson-Deyo score, primary site, and treatment type).

resultsHPV-positive patients with private insurance have improved overall survival compared with HPV-positive patients who are uninsured (hazard ratio [HR], 0.51, 95% CI, 0.41 to 0.63,

conclusionHPV status impact on overall survival for patients with OPSCC is influenced by socioeconomic factors including insurance status and treatment facility. A deeper understanding of these interactions is needed to improve equity of care for patients with OPSCC.

Indexed as

AlphapapillomavirusCarcinoma, Squamous CellHead and Neck NeoplasmsOropharyngeal NeoplasmsPapillomavirus InfectionsHumansPapillomaviridaeSocioeconomic FactorsSquamous Cell Carcinoma of Head and Neck

Identifiers

PMID33434083
PMCPMC8258012

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.