Evidence map›Paper›PMID 33434072›Full record

ReviewJournal of clinical oncology : official journal of the American Society of Clinical Oncology2021

Extending the Promise of Chimeric Antigen Receptor T-Cell Therapy Beyond Targeting CD19

Natalie S Grover, Nicholas Tschernia, Gianpietro Dotti, Barbara Savoldo

Abstract readReview
In one paragraph

Review in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Natalie S GroverLineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.ORCID 0000-0002-1346-3157
Nicholas TscherniaLineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.ORCID 0000-0002-2389-9974
Gianpietro DottiLineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Barbara SavoldoLineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.ORCID 0000-0002-7571-3887

Funding

UNC Oncology K12K12CA120780 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WILLIAM Y. KIM · 2007 to 2026
$9.6M
Enhancing cell therapy for brain tumorsU01CA239258 · NCI · CHILDREN'S RESEARCH INSTITUTE · PI BOLLARD, CATHERINE M., CRUZ, CONRAD RUSSELL YOUNG · 2018 to 2022
$3.2M
Tailoring CAR T cell therapy for Hodgkin LymphomaR01CA247497 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SAVOLDO, BARBARA · 2020 to 2024
$3.1M
Targeting the Ig-light chains with CAR-T cells in lymphoid tumorsR01CA193140 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DOTTI, GIANPIETRO · 2016 to 2020
$2.7M
Duke-UNC Chapel Hill Immunotherapy Training GrantT32CA211056 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHAO, NELSON J., SERODY, JONATHAN S. · 2017 to 2021
$2.2M
Cellular Immunotherapy of Ovarian CancerR01CA243543 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DOTTI, GIANPIETRO · 2019 to 2023
$2.0M
Targeting and Delivering CAR-Ts in GlioblastomaR21CA229938 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DOTTI, GIANPIETRO · 2019 to 2020
$372k
NCI NIH HHS K12 CA120780NCI NIH HHS R01 CA193140NCI NIH HHS R01 CA243543NCI NIH HHS R01 CA247497NCI NIH HHS R21 CA229938NCI NIH HHS T32 CA211056NCI NIH HHS U01 CA239258
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antigens, CD19B-LymphocytesClinical Trials, Phase I as TopicClinical Trials, Phase II as TopicHematologic NeoplasmsHumansImmunotherapy, AdoptiveAntigens, CD19CD19 molecule, human

Identifiers

PMID33434072
PMCPMC8462586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.