Evidence map›Paper›PMID 33434014›Full record

ArticleAnalytical chemistry2021

Comparing Stable Isotope Enrichment by Gas Chromatography with Time-of-Flight, Quadrupole Time-of-Flight, and Quadrupole Mass Spectrometry.

Ying Zhang, Bei Gao, Luis Valdiviez, Chao Zhu, Tara Gallagher, Katrine Whiteson, Oliver Fiehn

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Ying ZhangWest Coast Metabolomics Center, University of California, Davis, Davis, California 95616, United States.ORCID 0000-0002-6528-656X
Bei GaoDepartment of Medicine, University of California, San Diego, San Diego, California 92093, United States.ORCID 0000-0002-3321-2339
Luis ValdiviezWest Coast Metabolomics Center, University of California, Davis, Davis, California 95616, United States.
Chao ZhuCollege of Medicine & Nursing, Dezhou University, Dezhou 253023, Shandong, China.
Tara GallagherDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California 92697, United States.
Katrine WhitesonDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California 92697, United States.
Oliver FiehnWest Coast Metabolomics Center, University of California, Davis, Davis, California 95616, United States.ORCID 0000-0002-6261-8928
University of California, Davis · USUniversity of California, Irvine · USDezhou University · CNNanjing University of Information Science and Technology · CN

Funding

West Coast Central Comprehensive Metabolomics Resource Core (WC3MRC)U24DK097154 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIEHN, OLIVER · 2012 to 2017
$9.9M
West Coast Metabolomics Center for Compound IdentificationU2CES030158 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIEHN, OLIVER · 2018 to 2021
$4.1M
Dynamics of airway microbiota at pulmonary exacerbation in cystic fibrosisR01HL136647 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIPUMA, JOHN J · 2017 to 2020
$1.3M
NHLBI NIH HHS R01 HL136647NIDDK NIH HHS U24 DK097154NIEHS NIH HHS U2C ES030158
6 · The paper itself

Abstract

Stable isotope tracers are applied for in vivo and in vitro studies to reveal the activity of enzymes and intracellular metabolic pathways. Most often, such tracers are used with gas chromatography coupled to mass spectrometry (GC-MS) owing to its ease of operation and reproducible mass spectral databases. Differences in isotope tracer performance of the classic GC-quadrupole MS instrument and newer time-of-flight instruments are not well studied. Here, we used three commercially available instruments for the analysis of identical samples from a stable isotope labeling study that used [U-

Indexed as

Gas Chromatography-Mass SpectrometryIsotope LabelingMicrococcaceae

Identifiers

PMID33434014
PMCPMC10782559
OpenAlexW3120798364

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.