ArticleInternational ophthalmology2021
Degenerative lamellar macular holes: tractional development and morphological alterations.
Article in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Distinct postoperative anatomical outcomes between lamellar macular holes and epiretinal membrane foveoschisis.Eye (London, England) · 2026Article
- Changes in visual acuity and retinal microstructures following vitrectomy for lamellar macular hole.PloS one · 2026Article
- Modified inverted internal limiting membrane flap technique for lamellar macular hole.BMC ophthalmology · 2025Article
- Two cases of lamellar macular hole secondary to the rupture of the cystoid inner wall in patients with diabetic macular edema.International journal of ophthalmology · 2025Article
- Lamellar macular hole in highly myopic eyes and insights into its development, evolution, and treatment: a mini-review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Review
- [Lamellar macular holes-In the center of vitreomacular interface diseases : Pathophysiology, spontaneous courses and treatment concepts].Die Ophthalmologie · 2024Review
- Pathophysiology of Secondary Macular Hole in Rhegmatogenous Retinal Detachment.Investigative ophthalmology & visual science · 2023Article
- Quantitative Analyses of Retinal Traction Force and Metamorphopsia in Lamellar Macular Hole and Related Diseases.Ophthalmology science · 2023Article
- The development and evolution of lamellar macular hole in highly myopic eyes.Eye (London, England) · 2023Article
- Primary Lamellar Macular Holes: To Vit or Not to Vit.Journal of clinical medicine · 2022Review
- Modified surgical technique for lamellar macular holes with lamellar hole-associated epiretinal proliferation (LHEP).International ophthalmology · 2021Article
- Surgical Management of Full-Thickness Macular Holes Spontaneously Arising From Lamellar Macular Holes.Journal of vitreoretinal diseasesArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe development of degenerative lamellar macular holes (DLH) is largely unclear. This study was aimed at documenting with spectral-domain optical coherence tomography the tractional development and morphological alterations of DLH.
methodsA retrospective case series of 44 eyes of 44 patients is described.
resultsThe development of DLH is preceded for months or years by tractional deformations of the fovea due to the action of contractile epiretinal membranes (ERM) and/or the partially detached posterior hyaloid, or by cystoid macular edema (CME). DLH may develop after a tractional stretching and thickening of the foveal center, from a foveal pseudocyst, after a detachment of the foveola from the retinal pigment epithelium, a disruption of the foveal structure due to CME, and after surgical treatment of tractional lamellar or full-thickness macular holes (FTMH). The foveal configuration of a DLH can be spontaneously reestablished after short transient episodes of CME and a small FTMH. A DLH can evolve to a FTMH by traction of an ERM. Surgical treatment of a DLH may result in an irregular regeneration of the foveal center without photoreceptors.
conclusionsTractional forces play an important role in the development of DLH and in the further evolution to FTMH. It is suggested that a DLH is the result of a retinal wound repair process after a tractional disruption of the Müller cell cone and a degeneration of Henle fibers, to prevent a further increase in the degenerative cavitations.
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