Evidence map›Paper›PMID 33433626›Full record

ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2021

Adolescents and Young Adults Have Difficulty Understanding Nicotine Concentration Labels on Vaping Products Presented as mg/mL and Percent Nicotine.

Meghan E Morean, Olivia A Wackowski, Thomas Eissenberg, Cristine D Delnevo, Suchitra Krishnan-Sarin

Abstract read
In one paragraph

Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Preventive medicine reports · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. A Content Analysis of Nicotine Descriptors on the Front of Vape Packaging in the United Kingdom.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  9. Article
  10. Chemical Composition of Electronic Vaping Products From School Grounds in California.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  11. Prioritizing Common Terminology and Measures to Advance Research on Oral Nicotine Product Use.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  12. Impact of E-liquid Packaging on Vaping Product Perceptions Among Youth in England, Canada, and the United States: A Randomized Online Experiment.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  13. Article
  14. Use and Product Characteristics of "Tobacco Free Nicotine" E-Cigarettes Among Young Adults.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Meghan E MoreanYale School of Medicine, Department of Psychiatry, New Haven, CT, USA.ORCID 0000-0001-9159-5473
Olivia A WackowskiRutgers Center for Tobacco Studies, New Brunswick, NJ, USA.ORCID 0000-0003-4865-1155
Thomas EissenbergVirginia Commonwealth University, Department of Psychology, Richmond, VA, USA.
Cristine D DelnevoRutgers Center for Tobacco Studies, New Brunswick, NJ, USA.ORCID 0000-0001-9597-4307
Suchitra Krishnan-SarinYale School of Medicine, Department of Psychiatry, New Haven, CT, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Center for the Study of Tobacco Product Use and Addiction (YCSTP) Project 2: Addictive Threshold of Nicotine and the Impact of SweetenersU54DA036151 · NIDA · YALE UNIVERSITY · PI LISA M FUCITO · 2018 to 2026
$41.6M
USC Tobacco Center of Regulatory ScienceU54CA180905 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jessica Louise Barrington-Trimis, Adam Matthew Leventhal · 2018 to 2026
$39.0M
Project 4: Using a prospective cohort survey to test population-level predictions generated by Projects 1-3U54DA036105 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI FAGAN, PEBBLES · 2018 to 2022
$20.8M
Project 4: Comprehension of Health Risks in More and Less Arousing Affe p240-275P50CA180908 · NCI · OHIO STATE UNIVERSITY · PI SHIELDS, PETER G., WEWERS, MARY ELLEN · 2013 to 2017
$18.9M
Tobacco Industry Marketing CoreU54CA229973 · NCI · UNIVERSITY OF PENNSYLVANIA · PI STRASSER, ANDREW A · 2018 to 2022
$18.8M
Perceptions and Impact of Modified Risk Tobacco Product Communication MessagesR37CA222002 · NCI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI WACKOWSKI, OLIVIA · 2018 to 2023
$2.1M
FDA HHSNCATS NIH HHS UL1 TR001863NCI NIH HHS P50 CA180908NCI NIH HHS R37 CA222002NCI NIH HHS U54 CA180905NCI NIH HHS U54 CA229973NIDA NIH HHS U54 DA036105NIDA NIH HHS U54 DA036151
6 · The paper itself

Abstract

introductionE-cigarette e-liquid nicotine concentrations typically are labeled as mg/mL or percent nicotine. We examined whether these metrics accurately convey nicotine strength to young e-cigarette users and if youth can compare concentrations presented in mg/mL and percent nicotine. AIMS AND

methodsEight hundred and twenty-one adolescent and young adult e-cigarette users participated in the survey. Participants rated nicotine concentration strengths presented as mg/mL (0-60 mg/mL) and percent nicotine (0%-6%) from "no nicotine" to "very high nicotine." Participants also viewed pairs of nicotine concentrations (eg, 18 mg/mL vs. 5%) and indicated which concentration was stronger or if the concentrations were equivalent.

resultsOn average, participants correctly identified 5.92 (2.68) of 18 nicotine strengths, correctly identifying strengths labeled as mg/mL (3.47 [2.03]) more often than percent nicotine (2.45 [1.38], p < .001). Excluding nicotine-free, participants rated concentrations presented as mg/mL as stronger, more addictive, and more harmful than equivalent concentrations presented as percent nicotine. Participants seldom correctly identified that one concentration was stronger or that both were equivalent (7.58 [5.88] of 19 pairings), although they more often correctly identified the stronger concentration when it was presented in mg/mL (4.02 [SD = 3.01]) than in percent nicotine (2.53 [2.73], p < .001). The most consistent predictor of correct answers on these tasks was familiarity with using both products labeled as mg/mL and labeled as percent nicotine.

conclusionsYoung e-cigarette users had difficulty understanding nicotine concentrations labeled using the most common metrics, raising concerns about inadvertent exposure to high nicotine levels and suggesting that a more intuitive labeling approach is needed. IMPLICATIONS: This study extends prior work showing that young e-cigarette users often are uncertain whether the e-liquids they use contain nicotine by demonstrating that adolescents and young adults have difficulty understanding nicotine concentrations labeled using the two most common metrics (mg/mL and percent nicotine). Errors generally underestimated nicotine strength, and users were not able to accurately compare nicotine concentrations presented as mg/mL and percent nicotine. Difficulty understanding labeling metrics persisted even after accounting for user characteristics like age and vaping experience, suggesting that a novel, easy to understand labeling system is needed to convey information about nicotine strength accurately.

Indexed as

Electronic Nicotine Delivery SystemsTobacco ProductsVapingAdolescentHumansNicotineSurveys and QuestionnairesYoung AdultNicotine

Identifiers

PMID33433626
PMCPMC8496508

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.