Evidence map›Paper›PMID 33433001›Full record

ArticleAlcoholism, clinical and experimental research2021

Validity and Reliability of Executive Function Measures in Children With Heavy Prenatal Alcohol Exposure: Correspondence Between Multiple Raters and Laboratory Measures.

Gemma A Bernes, Miguel Villodas, Claire D Coles, Julie A Kable, Philip A May, Wendy O Kalberg, Elizabeth R Sowell, Kenneth L Jones, Edward P Riley, Sarah N Mattson and 1 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Alcoholism, clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Gemma A BernesCenter for Behavioral Teratology, San Diego State University, San Diego, CA, USA.
Miguel VillodasDepartment of Psychology, San Diego State University, San Diego, CA, USA.
Claire D ColesDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0003-3399-6644
Julie A KableDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0001-5008-0887
Philip A MayDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina Nutrition Research Institute, Kannapolis, NC, USA.
Wendy O KalbergCenter on Alcoholism, Substance Abuse, and Addictions, University of New Mexico, Albuquerque, NM, USA.
Elizabeth R SowellDepartment of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Kenneth L JonesDepartment of Pediatrics, University of California, San Diego School of Medicine, San Diego, CA, USA.
Edward P RileyCenter for Behavioral Teratology, San Diego State University, San Diego, CA, USA.
Sarah N MattsonCenter for Behavioral Teratology, San Diego State University, San Diego, CA, USA.ORCID 0000-0001-8499-9605
CIFASD
San Diego State University · USEmory University · USUniversity of New Mexico · USUniversity of San Diego · USUniversity of Southern California · US

Funding

Cross-Cultural Assessment of FASDU24AA014811 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY · 2003 to 2026
$13.1M
FASD in San Diego and Moscow (U01 Research Project)U01AA014834 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI SARAH N MATTSON WELLER · 2003 to 2026
$12.4M
FASD Diagnostic Telemedicine ResourceU24AA014815 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Lauren Gist, SARAH N MATTSON WELLER · 2003 to 2026
$5.6M
NIAAA NIH HHS U01 AA014834NIAAA NIH HHS U24 AA014811NIAAA NIH HHS U24 AA014815
6 · The paper itself

Abstract

backgroundRating scales are designed to complement traditional performance-based measures, and both can provide useful information about the functioning of youth with histories of prenatal alcohol exposure. Few studies, however, have compared ratings from multiple informants or the relationship between these subjective rating scale scores and the objective results from laboratory performance-based scales.

methodsThe current study addressed both of these questions in 3 study groups: children with histories of prenatal alcohol exposure (n = 47), attention-deficit/hyperactivity disorder (ADHD; n = 41), and typically developing controls (CON; n = 73). All subjects completed a standardized neuropsychological test battery, including laboratory measures of executive functioning and a self-report measure of executive function behaviors. Parents and teachers completed corresponding rating scales of executive function behaviors for each subject. This study assessed the relationship between these behavior rating scales and corresponding neuropsychological tests, and interrater agreement among the multiple informants.

resultsWeak correlations were found between the rating scales and laboratory measures, indicating poor convergent validity for the behavior rating scale. Interrater reliability was found but it differed by group. Agreement was found between parent and teacher ratings for children with prenatal alcohol exposure, whereas teacher-child agreement was found for those with ADHD.

conclusionsFindings from this study indicate that behavior ratings can be used to supplement laboratory measures but may not be measuring cognitive abilities regardless of whether a clinical diagnosis is present. A multimethod approach should be used when measuring skills in this domain. This was one of the first studies to examine cross-informant agreement in a sample of children with prenatal alcohol exposure. Further research is necessary to understand why interrater agreement differed for children with prenatal alcohol exposure and those with ADHD.

Indexed as

AdolescentAlcohol DrinkingAttention Deficit Disorder with HyperactivityBehavior Rating ScaleChildClinical Laboratory TechniquesExecutive FunctionFemaleFetal Alcohol Spectrum DisordersHumansMaleNeuropsychological TestsPregnancyPrenatal Exposure Delayed EffectsReproducibility of ResultsBehavior Rating ScalesExecutive FunctionFetal Alcohol Spectrum DisordersInterrater AgreementValidity

Identifiers

PMID33433001
PMCPMC7969422
OpenAlexW3118418259

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.