ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2021
Sex differences in deterioration of sleep properties associated with aging: a 12-year longitudinal cohort study.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Chronic Insufficient Sleep in Women Impairs Insulin Sensitivity Independent of Adiposity Changes: Results of a Randomized Trial.Diabetes care · 2024Trial
- Sleep pattern differences in women at midlife: a large-scale multi-country smartwatch study (SONAR).Sleep · 2026Article
- Multidimensional Physiological and Gut Microbiome Profiling Identifies Subtle Physiological Patterns in an Apparently Healthy Aging Indian Cohort: A Cross-Sectional Observational Study.Microorganisms · 2026Article
- Sex Differences in Sleep Duration and Quality: Implications for Hypertension Risk.Current hypertension reports · 2026Review
- Article
- Self-Efficacy is Key: Examining the Role of Motivation to Engage in Healthy Lifestyle Behaviors for Dementia Prevention in Midlife.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026Article
- Sleep disturbances and Alzheimer's disease: a multiscale approach from exposome to neurobiology and precision medicine.GeroScience · 2026Review
- Seasonal variation in sleep apnea and other sleep parameters from diagnostic polysomnography data, 2003-2024.Communications health · 2026Article
- Sleeping for two: a cross-sectional study on associations between objectively measured sleep during early to mid-pregnancy and maternal and fetal outcomes and inflammatory biomarker profiles.BMC pregnancy and childbirth · 2025Article
- The influence of sex on sleep characteristics in the adult and older adult population: findings from the EPISONO sleep study.Frontiers in sleep · 2025Article
- Sleep Health Analysis Through Sleep Symptoms in 35,808 Individuals Across Age and Sex Differences: Comparative Symptom Network Study.JMIR public health and surveillance · 2024Article
- Sex Differences in the Role of Sleep on Cognition in Older Adults.medRxiv : the preprint server for health sciences · 2024Article
- Longitudinal Trends in Sleep and Related Factors Among South Korean Adults From 2009 to 2018.Journal of clinical neurology (Seoul, Korea) · 2023Article
- Perceived quality of sleep across the menopausal transition: A retrospective cohort study.Health science reports · 2023Article
- COVID-19 and Sleep Disturbances: A Literature Review of Clinical Evidence.Medicina (Kaunas, Lithuania) · 2023Review
- Burden of Sleep Disturbance During COVID-19 Pandemic: A Systematic Review.Nature and science of sleep · 2021Review
- Couple Relationships Are Associated With Increased REM Sleep-A Proof-of-Concept Analysis of a Large Dataset Using Ambulatory Polysomnography.Frontiers in psychiatry · 2021Article
- Self-Reported Sleeping Time Effects on Physical Performance and Body Composition Among Spanish Older Adults: EXERNET-Elder 3.0 study.Gerontology & geriatric medicineArticle
- Multidimensional Sleep and Self-Rated Physical Health and Depressive Symptoms Among Retired Older Adults: A Sex-Stratified Analysis.Behavioral sleep medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesThe sleep patterns of humans are greatly influenced by age and sex and have various effects on overall health as they change continuously during the lifespan. We investigated age-dependent changes in sleep properties and their relation to sex in middle-aged individuals.
methodsWe analyzed data from 2,640 participants (mean age of 49.8 ± 6.8 years at baseline, 50.6% women) in the Korean Genome and Epidemiology Study, which assessed sleep habits using the Pittsburgh Sleep Quality Index and other clinical characteristics. We analyzed the sleep habit changes that occurred between baseline and a follow-up point (mean interval: 12.00 ± 0.16 years). Associations of age and sex with 9 sleep characteristics were evaluated.
resultsAge was associated with most of the sleep characteristics cross-sectionally and longitudinally (P < .05), except for the time in bed at baseline (P = .455) and change in sleep duration (P = .561). Compared with men, women had higher Pittsburgh Sleep Quality Index scores, shorter time in bed, shorter sleep duration, and longer latency at baseline (P ≤ .001). Longitudinal deterioration in Pittsburgh Sleep Quality Index score, habitual sleep efficiency, duration, and latency was more prominent in women (P < .001). The sex differences in these longitudinal sleep changes were mainly noticeable before age 60 years (P < .05). Worsening of Pittsburgh Sleep Quality Index scores, habitual sleep efficiency, and latency was most evident in perimenopausal women. Men presented with greater advancement of chronotype (P = .006), with the peak sex-related difference occurring when they were in their late 40s (P = .048).
conclusionsAging is associated with substantial deterioration in sleep quantity and quality as well as chronotype advancement, with the degree and timing of these changes differing by sex.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.