Evidence map›Paper›PMID 33432742›Full record

ArticleWorld psychiatry : official journal of the World Psychiatric Association (WPA)2021

An organization- and category-level comparison of diagnostic requirements for mental disorders in ICD-11 and DSM-5.

Michael B First, Wolfgang Gaebel, Mario Maj, Dan J Stein, Cary S Kogan, John B Saunders, Vladimir B Poznyak, Oye Gureje, Roberto Lewis-Fernández, Andreas Maercker and 13 more

Abstract read
In one paragraph

Article in World psychiatry : official journal of the World Psychiatric Association (WPA), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  15. Antidepressant Augmentation of Antipsychotic Treatment in Schizophrenia: A Narrative Review.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
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33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Michael B FirstDepartment of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Wolfgang GaebelDepartment of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Mario MajDepartment of Psychiatry, University of Campania "L. Vanvitelli", Naples, Italy.
Dan J SteinDepartment of Psychiatry, University of Cape Town and South African Medical Research Council Unit on Risk and Resilience in Mental Disorders, Cape Town, South Africa.
Cary S KoganSchool of Psychology, University of Ottawa, Ottawa, ON, Canada.
John B SaundersCentre for Youth Substance Abuse Research, University of Queensland, Brisbane, QLD, Australia.
Vladimir B PoznyakDepartment of Mental Health and Substance Use, World Health Organization, Geneva, Switzerland.
Oye GurejeDepartment of Psychiatry, University of Ibadan, Ibadan, Nigeria.
Roberto Lewis-FernándezDepartment of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Andreas MaerckerDepartment of Psychology, University of Zurich, Zurich, Switzerland.
Chris R BrewinResearch Department of Clinical, Educational and Health Psychology, University College London, London, UK.
Marylene CloitreNational Center for PTSD Dissemination and Training Division, VA Palo Alto Health Care System, Palo Alto, CA, USA.
Angelica ClaudinoDepartment of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.
Kathleen M PikeDepartment of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Gillian BairdNewcomen Centre, Evelina Children's Hospital, Guys & St. Thomas NHS Foundation Trust, London, UK.
David SkuseBrain and Behaviour Science Unit, Institute of Child Health, University College London, London, UK.
Richard B KruegerDepartment of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Peer BrikenInstitute for Sex Research, Sexual Medicine and Forensic Psychiatry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Jeffrey D BurkeDepartment of Psychological Sciences, University of Connecticut, Storrs, CT, USA.
John E LochmanDepartment of Psychology, University of Alabama, Tuscaloosa, AL, USA.
Spencer C EvansUniversity of Miami, Coral Gables, FL, USA.
Douglas W WoodsOffiice of the Provost and Department of Psychology, Marquette University, Milwaukee, WI, USA.
Geoffrey M ReedDepartment of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA.

Funding

World Health Organization 001
6 · The paper itself

Abstract

In 2013, the American Psychiatric Association (APA) published the 5th edition of its Diagnostic and Statistical Manual of Mental Disorders (DSM-5). In 2019, the World Health Assembly approved the 11th revision of the International Classification of Diseases (ICD-11). It has often been suggested that the field would benefit from a single, unified classification of mental disorders, although the priorities and constituencies of the two sponsoring organizations are quite different. During the development of the ICD-11 and DSM-5, the World Health Organization (WHO) and the APA made efforts toward harmonizing the two systems, including the appointment of an ICD-DSM Harmonization Group. This paper evaluates the success of these harmonization efforts and provides a guide for practitioners, researchers and policy makers describing the differences between the two systems at both the organizational and the disorder level. The organization of the two classifications of mental disorders is substantially similar. There are nineteen ICD-11 disorder categories that do not appear in DSM-5, and seven DSM-5 disorder categories that do not appear in the ICD-11. We compared the Essential Features section of the ICD-11 Clinical Descriptions and Diagnostic Guidelines (CDDG) with the DSM-5 criteria sets for 103 diagnostic entities that appear in both systems. We rated 20 disorders (19.4%) as having major differences, 42 disorders (40.8%) as having minor definitional differences, 10 disorders (9.7%) as having minor differences due to greater degree of specification in DSM-5, and 31 disorders (30.1%) as essentially identical. Detailed descriptions of the major differences and some of the most important minor differences, with their rationale and related evidence, are provided. The ICD and DSM are now closer than at any time since the ICD-8 and DSM-II. Differences are largely based on the differing priorities and uses of the two diagnostic systems and on differing interpretations of the evidence. Substantively divergent approaches allow for empirical comparisons of validity and utility and can contribute to advances in the field.

Indexed as

anxiety and fear-related disordersclassificationdiagnosisdisorders due to substance usedisorders specifically associated with stressDSM-5ICD-11mental disordersmood disordersneurocognitive disordersneurodevelopmental disorderspersonality disordersprimary psychotic disorders

Identifiers

PMID33432742
PMCPMC7801846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.