Evidence map›Paper›PMID 33432599›Full record

ArticleEuropean journal of clinical investigation2021

The Iliofemoral tortuosity score predicts access and bleeding complications during transfemoral transcatheter aortic valve replacement: DataData from the VIenna Cardio Thoracic aOrtic valve registrY (VICTORY).

Markus Mach, Thomas Poschner, Waseem Hasan, Philipp Szalkiewicz, Martin Andreas, Bernhard Winkler, Stephanie Geisler, Daniela Geisler, Piotr N Rudziński, Victoria Watzal and 4 more

Abstract read
In one paragraph

Article in European journal of clinical investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Computed tomography derived anatomical predictors of vascular access complications following transfemoral transcatheter aortic valve implantation: A systematic review.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2024
    Pooled it
  2. Peripheral vessel tortuosity index and prognosis in patients undergoing transcatheter aortic valve implantation.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
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  7. Navigating Treble Clef Aorta: A Challenge for Transfemoral Transcatheter Aortic Valve Replacement-A Case Report.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Markus MachDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-3184-4914
Thomas PoschnerDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Waseem HasanDepartment of Cardio-Vascular Surgery, Heart Team Vienna, Hospital Hietzing, and the Karl Landsteiner Institute for Cardio-Vascular Research, Vienna, Austria.ORCID https://orcid.org/0000-0002-4740-0197
Philipp SzalkiewiczDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Martin AndreasDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Bernhard WinklerDepartment of Cardio-Vascular Surgery, Heart Team Vienna, Hospital Hietzing, and the Karl Landsteiner Institute for Cardio-Vascular Research, Vienna, Austria.
Stephanie GeislerDepartment of Cardio-Vascular Surgery, Heart Team Vienna, Hospital Hietzing, and the Karl Landsteiner Institute for Cardio-Vascular Research, Vienna, Austria.
Daniela GeislerDepartment of Cardio-Vascular Surgery, Heart Team Vienna, Hospital Hietzing, and the Karl Landsteiner Institute for Cardio-Vascular Research, Vienna, Austria.ORCID https://orcid.org/0000-0001-7930-344X
Piotr N RudzińskiDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Victoria WatzalDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Andreas StrouhalVienna North Hospital - Clinic Floridsdorf and the Karl Landsteiner Institute for Cardiovascular and Critical Care Research, Vienna, Austria.
Christopher AdlbrechtVienna North Hospital - Clinic Floridsdorf and the Karl Landsteiner Institute for Cardiovascular and Critical Care Research, Vienna, Austria.
Georg Delle-KarthVienna North Hospital - Clinic Floridsdorf and the Karl Landsteiner Institute for Cardiovascular and Critical Care Research, Vienna, Austria.
Martin GrabenwögerDepartment of Cardio-Vascular Surgery, Heart Team Vienna, Hospital Hietzing, and the Karl Landsteiner Institute for Cardio-Vascular Research, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArterial tortuosity is linked to a higher risk of adverse clinical events after transfemoral transcatheter aortic valve replacement (TF-TAVR). Currently, there are no assessment tools that can quantify this variable in three-dimensional space. This study investigated the impact of novel scoring methods of iliofemoral tortuosity on access and bleeding complications after TF-TAVR.

methodsThe main access vessel was assessed between the aortoiliacal and femoral bifurcation in preoperative multislice computed tomography scans of 240 consecutive patients undergoing TF-TAVR. Tortuosity was assessed by three methods: largest single angle, sum of all angles, and iliofemoral tortuosity (IFT) score [((true vessel length/ideal vessel length)-1)*100]. The primary study endpoint was a composite of access and bleeding complications. The secondary study endpoints were 30-day mortality and long-term survival.

resultsAmong 240 patients, only the IFT score demonstrated a good positive correlation with the composite primary endpoint of access and bleeding complications (P = 0.031). A higher incidence of access and bleeding complications was found in patients with a higher IFT score (56 [36.8%] vs 17 [19.3%]; P = 0.003). In a multivariate logistic regression analysis, only the IFT score was a significant predictor of the primary endpoint (OR: 2.11; 95% CI: 1.09-4.05; P = 0.026).

conclusionVascular tortuosity is an underestimated risk factor during TF-TAVR. The IFT score is a valuable tool in risk stratification before TF-TAVR, predicting periprocedural access and bleeding complications.

Indexed as

AgedAged, 80 and overAortaAortic DissectionBlood Loss, SurgicalFemaleFemoral ArteryHumansIliac ArteryIntraoperative ComplicationsMaleMultidetector Computed TomographyPostoperative HemorrhageTranscatheter Aortic Valve ReplacementVascular System InjuriesaccessbleedingTAVITAVRtortuositytranscatheter

Identifiers

PMID33432599
PMCPMC8243921

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.