ReviewCurrent treatment options in oncology2021
The Importance of Prognostication: Impact of Prognostic Predictions, Disclosures, Awareness, and Acceptance on Patient Outcomes.
Review in Current treatment options in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Improving communication of prognostic uncertainty in advanced illness: a realist review.BMJ open · 2026Pooled it
- Prevalence and prognostic value of baseline sarcopenia in hematologic malignancies: a systematic review.Frontiers in oncology · 2023Pooled it
- Perceptions of prognosis and end-of-life care outcomes in patients with advanced lung and gastrointestinal cancer.Palliative medicine · 2023Trial
- Association between family-perceived quality of death and dying, prognostic awareness, and end-of-life discussions in five common diseases: a nationwide mortality follow-back study.BMC palliative care · 2026Article
- Prognostic disclosure in metastatic breast cancer: a scoping review.The oncologist · 2026Article
- Prognostic communication preferences of cancer patients: A hybrid concept analysis.International journal of nursing sciences · 2026Article
- Top of the license practice or out of our scope? A qualitative analysis of social workers' role in cultivating prognostic awareness on hospital palliative care teams.BMC palliative care · 2026Article
- Advances in End-of-Life Care in Canada: Implications for Oncology Nursing.Current oncology (Toronto, Ont.) · 2026Review
- Prognostic awareness in family caregivers of patients with terminal illness: a scoping review.BMJ open · 2025Article
- When would I be surprised? Variability in predicted probability of survival for being "surprised" and "not surprised" to the surprise question.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Prognostic Disclosure in Metastatic Breast Cancer: Protocol for a Scoping Review.JMIR research protocols · 2025Article
- Accurate prognostic awareness is associated with increased emotional distress in Latino patients with advanced cancer.Palliative & supportive care · 2025Article
- Correlates of Perceived Illness Severity and Terminality in Advanced Lung and Prostate Cancer.Journal of pain and symptom management · 2025Article
- Effects of oral intake, symptom severity, and sex difference on cancer patient prognosis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Observational
- Revisiting the Role of Long Non-coding RNA PSMA3-AS1 in Human Cancers: Current Evidence and Future Directions.Current pharmaceutical design · 2025Review
- Depression, performance status, and discontinued treatment mediate an association of curability belief with prognosis in advanced cancer patients.Scientific reports · 2024Article
- Clinicians' Perspectives on the Telehealth Serious Illness Care Program for Older Adults With Myeloid Malignancies: Single-Arm Pilot Study.JMIR formative research · 2024Article
- Mapping the landscape of histomorphological cancer phenotypes using self-supervised learning on unannotated pathology slides.Nature communications · 2024Article
- Preparing for Cancer: A Qualitative Study of Hispanic Patient and Caregiver Needs.Healthcare (Basel, Switzerland) · 2024Article
- The trajectory of prognostic cognition in patients with advanced cancer: is the traditional advance care planning approach desirable for patients?Japanese journal of clinical oncology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
opinion statementIn the advanced cancer setting, patients, families, and clinicians are often confronted with an uncertain future regarding treatment outcomes and survival. Greater certainty on what to expect can enhance decision-making for many personal and healthcare issues. Although 70-90% of patients with advanced cancer desire open and honest prognostic disclosure, a small proportion do not want to know. Approximately half of patients with advanced cancer have an inaccurate understanding of their illness, which could negatively impact their decision-making. In this review, we use a conceptual framework to highlight 5 key steps along the prognostic continuum, including (1) prognostic formulation, (2) prognostic disclosure, (3) prognostic awareness, (4) prognostic acceptance, and (5) prognosis-based decision-making. We shall summarize the impact of prognostic predictions, disclosure, awareness, and acceptance on various patient and caregiver outcomes, such as hope, trust, anxiety, depression, chemotherapy use, and care planning. Based on where the patient is at along the prognostic continuum, we propose 5 different subgroups (avoidance: "I don't want to know"; discordant, "I never wanted to know"; anxious, "I don't know what's happening"; concerned, "I don't like this"; acceptance, "I know how to plan ahead"). Although prognostication is not necessarily a linear process, recognizing where the patient is at cognitively and emotionally along the prognostic continuum may allow clinicians to provide personalized interventions, such as specialist palliative care and psychology referral, towards personalizing prognostic disclosure, enhancing prognostic awareness, increasing prognostic acceptance, and supporting decision-making and, ultimately, improving patient outcomes.
Indexed as
Identifiers
33432524What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.