Evidence map›Paper›PMID 33432475›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2021

Increased body mass index, age, and left atrial size are associated with altered intracardiac atrial electrograms in persistent atrial fibrillation patients.

Isaac L Goldenthal, Edward J Ciaccio, Robert R Sciacca, Hasan Garan, Angelo B Biviano

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Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Isaac L GoldenthalInternal Medicine, Division of Cardiology, Columbia University Irving Medical Center, 622 W 168th St, New York, NY, 10032, USA.
Edward J CiaccioInternal Medicine, Division of Cardiology, Columbia University Irving Medical Center, 622 W 168th St, New York, NY, 10032, USA.
Robert R SciaccaInternal Medicine, Division of Cardiology, Columbia University Irving Medical Center, 622 W 168th St, New York, NY, 10032, USA.
Hasan GaranInternal Medicine, Division of Cardiology, Columbia University Irving Medical Center, 622 W 168th St, New York, NY, 10032, USA.
Angelo B BivianoInternal Medicine, Division of Cardiology, Columbia University Irving Medical Center, 622 W 168th St, New York, NY, 10032, USA. ab542@columbia.edu.
Columbia University Irving Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are limited studies evaluating whether atrial fibrillation (AF) patients with increased BMI, age, and left atrial (LA) size have altered intracardiac electrogram (EGM) morphology.

methodsWe analyzed left atrial intracardiac EGMs acquired during invasive electrophysiology study in 54 patients with AF. EGM correlations were assessed among AF risk factors including age, left atrial size, and BMI.

resultsBMI correlated positively with DF (r

conclusionsEGM morphology of AF patients with increased BMI, older age, and an enlarged LA possessed decreased amplitude and decreased width and increased DF and MP. These findings suggest that atrial remodeling due to increased age, LA size, and BMI is associated with differences in local atrial activation, decreased refractoriness, and more heterogeneous activation. These novel findings point out clinical risk factors for atrial fibrillation that may affect electrogram characteristics.

Indexed as

Atrial FibrillationAtrial RemodelingAgedBody Mass IndexElectrophysiologic Techniques, CardiacHeart AtriaHumansMaleAblationageAtrial ElectrogramAtrial fibrillationBMILeft atrial Size

Identifiers

PMID33432475
OpenAlexW3120917899

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.