Evidence map›Paper›PMID 33432454›Full record

ArticleTranslational stroke research2021

Combined Perfusion and Permeability Imaging Reveals Different Pathophysiologic Tissue Responses After Successful Thrombectomy.

Arne Potreck, Matthias A Mutke, Charlotte S Weyland, Johannes A R Pfaff, Peter A Ringleb, Sibu Mundiyanapurath, Markus A Möhlenbruch, Sabine Heiland, Mirko Pham, Martin Bendszus and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Translational stroke research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Progressive microvascular failure in acute ischemic stroke: A systematic review, meta-analysis, and time-course analysis.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
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  10. Quantitative imaging outperforms No-reflow in predicting functional outcomes in a translational stroke model.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
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  15. Hyperperfusion profiles after recanalization differentially associate with outcomes in a rat ischemic stroke model.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
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  18. Post-ischemic hyperemia following endovascular therapy for acute stroke is associated with lesion growth.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
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  19. Review
  20. Seizures and epilepsy in patients with ischaemic stroke.Neurological research and practice · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Arne Potreck *Department of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
Matthias A Mutke *Department of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
Charlotte S WeylandDepartment of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
Johannes A R PfaffDepartment of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
Peter A RinglebDepartment of Neurology, Heidelberg University Hospital, Heidelberg, Germany.
Sibu MundiyanapurathDepartment of Neurology, Heidelberg University Hospital, Heidelberg, Germany.
Markus A MöhlenbruchDepartment of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
Sabine HeilandDepartment of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
Mirko PhamDepartment of Neuroradiology, Würzburg University Hospital, Würzburg, Germany.
Martin BendszusDepartment of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
Angelika HoffmannDepartment of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany. angelika.hoffmann@med.uni-heidelberg.de.ORCID 0000-0003-4552-0694
Heidelberg University · DEUniversitätsklinikum Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite successful recanalization of large-vessel occlusions in acute ischemic stroke, individual patients profit to a varying degree. Dynamic susceptibility-weighted perfusion and dynamic T1-weighted contrast-enhanced blood-brain barrier permeability imaging may help to determine secondary stroke injury and predict clinical outcome. We prospectively performed perfusion and permeability imaging in 38 patients within 24 h after successful mechanical thrombectomy of an occlusion of the middle cerebral artery M1 segment. Perfusion alterations were evaluated on cerebral blood flow maps, blood-brain barrier disruption (BBBD) visually and quantitatively on k

Indexed as

Brain IschemiaStrokeHumansPerfusionPermeabilityThrombectomyTreatment OutcomeHyperperfusionMechanical thrombectomyPerfusion imagingPermeability imagingSecondary stroke injury

Identifiers

PMID33432454
PMCPMC8421283
OpenAlexW3120115854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.