Evidence map›Paper›PMID 33432421›Full record

ArticleJA clinical reports2021

Anesthetic management for a patient with myotonic dystrophy with remimazolam.

Yasuhiro Morimoto, Aya Yoshimatsu, Manabu Yoshimura

Open access · goldAbstract read
In one paragraph

Article in JA clinical reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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  5. Remimazolam: a comprehensive review.Anaesthesiology intensive therapy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yasuhiro MorimotoDepartment of Anesthesia, Ube Industries Central Hospital, 750 Nishikiwa Ube, Yamaguchi, 755-0151, Japan. yasumorimo@gmail.com.ORCID http://orcid.org/0000-0001-7658-2834
Aya YoshimatsuDepartment of Anesthesia, Ube Industries Central Hospital, 750 Nishikiwa Ube, Yamaguchi, 755-0151, Japan.
Manabu YoshimuraDepartment of Anesthesia, Ube Industries Central Hospital, 750 Nishikiwa Ube, Yamaguchi, 755-0151, Japan.
Ube (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with myotonic dystrophy may have increased sensitivity to drugs used for anesthesia. We successfully managed general anesthesia in a patient with myotonic dystrophy using a novel intravenous anesthetic, remimazolam. CASE PRESENTATION: The patient was a 46-year-old man, 169 cm in height, and weighing 60 kg. He was diagnosed with myotonic dystrophy 5 years previously. Phacoemulsification for both eyes was scheduled under general anesthesia. Anesthesia was induced with remimazolam 6 mg/kg/h for 1 min and maintained by continuous infusion at 0.25 mg/kg/h during surgery, a 1/4 dose of the standard infusion rate, as indexed by a bispectral index (BIS). Six minutes after remimazolam discontinuation, the patient opened his eyes on verbal command with sufficient spontaneous respiration. Flumazenil (0.2 mg) was administered to boost the patient's recovery.

conclusionIn addition to the short-acting anesthetic remimazolam, the presence of the antagonist flumazenil enabled complete recovery from anesthesia, without postoperative complications.

Indexed as

FlumazenilMyotonic dystrophyRemimazolam

Identifiers

PMID33432421
PMCPMC7801543
OpenAlexW3119541216

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.