Evidence map›Paper›PMID 33432138›Full record

ArticleThe ISME journal2021

Reconfiguration of metabolic fluxes in Pseudomonas putida as a response to sub-lethal oxidative stress.

Pablo I Nikel, Tobias Fuhrer, Max Chavarría, Alberto Sánchez-Pascuala, Uwe Sauer, Víctor de Lorenzo

Open access · hybridAbstract read
In one paragraph

Article in The ISME journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.

  1. Pooled it
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  6. Natural and Synthetic Metabolic Architectures.Chembiochem : a European journal of chemical biology · 2026
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  9. Going beyond size: exploring the metabolic burden inSynthetic biology (Oxford, England) · 2026
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  12. Synthetic CmBio · 2025
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  13. Article
  14. Article
  15. Review
  16. Article
  17. Genome streamlining ofmSystems · 2024
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 5 countries.

Pablo I NikelThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800 Kgs, Lyngby, Denmark. pabnik@biosustain.dtu.dk.ORCID http://orcid.org/0000-0002-9313-7481
Tobias FuhrerInstitute of Molecular Systems Biology, ETH Zurich, 8093, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-5006-6874
Max ChavarríaEscuela de Química & CIPRONA, Universidad de Costa Rica, 2060, San José, Costa Rica.ORCID http://orcid.org/0000-0001-5901-3576
Alberto Sánchez-PascualaDepartment of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, 35043, Marburg, Germany.ORCID http://orcid.org/0000-0003-2359-8626
Uwe SauerInstitute of Molecular Systems Biology, ETH Zurich, 8093, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-5923-0770
Víctor de LorenzoSystems and Synthetic Biology Program, Centro Nacional de Biotecnología (CNB-CSIC), 28049, Madrid, Spain. vdlorenzo@cnb.csic.es.ORCID http://orcid.org/0000-0002-6041-2731
ETH Zurich · CHCentro Nacional de Biotecnología · ESMax Planck Institute for Terrestrial Microbiology · DENovo Nordisk Foundation · DKUniversidad de Costa Rica · CR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a frequent inhabitant of sites polluted with toxic chemicals, the soil bacterium and plant-root colonizer Pseudomonas putida can tolerate high levels of endogenous and exogenous oxidative stress. Yet, the ultimate reason of such phenotypic property remains largely unknown. To shed light on this question, metabolic network-wide routes for NADPH generation-the metabolic currency that fuels redox-stress quenching mechanisms-were inspected when P. putida KT2440 was challenged with a sub-lethal H

Indexed as

Pseudomonas putidaHydrogen PeroxideMetabolic Networks and PathwaysOxidation-ReductionOxidative StressHydrogen Peroxide

Identifiers

PMID33432138
PMCPMC8163872
OpenAlexW3119857353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.