Evidence map›Paper›PMID 33431985›Full record

ArticleScientific reports2021

Searching for a UV-filter in the eyes of high-flying birds.

Malgorzata Zawadzka, Beatrix Ràcz, Dario Ambrosini, Carl Henrik Görbitz, Jens Preben Morth, Alistair L Wilkins, Anja Østeby, Katja Benedikte Prestø Elgstøen, Elsa Lundanes, Frode Rise and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Significance of Singlet Oxygen Molecule in Pathologies.International journal of molecular sciences · 2023
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Malgorzata ZawadzkaDepartment of Chemistry, University of Oslo, Blindern, Post Box 1033, 0315, Oslo, Norway.
Beatrix RàczDepartment of Chemistry, University of Oslo, Blindern, Post Box 1033, 0315, Oslo, Norway.
Dario AmbrosiniDepartment of Chemistry, University of Oslo, Blindern, Post Box 1033, 0315, Oslo, Norway.
Carl Henrik GörbitzDepartment of Chemistry, University of Oslo, Blindern, Post Box 1033, 0315, Oslo, Norway.
Jens Preben MorthEnzyme and Protein Chemistry, Section for Protein Chemistry and Enzyme Technology, Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, 2800, Kgs. Lyngby, Denmark.
Alistair L WilkinsFaculty of Science and Engineering, The University of Waitato, Gate 1 Knighton Road, Private Bag 3105, Hamilton, 3240, New Zealand.
Anja ØstebyDepartment of Medical Biochemistry, Oslo University Hospital Rikshospitalet, Nydalen, PO Box 4950, 0424, Oslo, Norway.
Katja Benedikte Prestø ElgstøenDepartment of Medical Biochemistry, Oslo University Hospital Rikshospitalet, Nydalen, PO Box 4950, 0424, Oslo, Norway.
Elsa LundanesDepartment of Chemistry, University of Oslo, Blindern, Post Box 1033, 0315, Oslo, Norway.
Frode RiseDepartment of Chemistry, University of Oslo, Blindern, Post Box 1033, 0315, Oslo, Norway.
Amund RingvoldDepartment of Ophthalmology, Oslo University Hospital, Ullevål, Nydalen, Postbox 4956, 0424, Oslo, Norway. a.d.ringvold@medisin.uio.no.
Steven Ray WilsonDepartment of Chemistry, University of Oslo, Blindern, Post Box 1033, 0315, Oslo, Norway. stevenw@kjemi.uio.no.ORCID 0000-0002-9755-1188
University of Oslo · NOOslo University Hospital · NOTechnical University of Denmark · DKUniversity of Waikato · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The eye lens is a unique organ as no cells can be replaced throughout life. This makes it decisive that the lens is protected against damaging UV-radiation. An ultraviolet (UV)-absorbing compound of unknown identity is present in the aqueous humor of geese (wild and domestic) and other birds flying at high altitudes. A goose aqueous humor extract, that was believed to contain the UV protective compound which was designated as "compound X", was fractionated and examined using a variety of spectroscopic techniques including LC-MS and high field one- and two dimensional-NMR methods. A series of compounds were identified but none of them appeared to be the UV protective "compound X". It may be that the level of the UV protective compound in goose aqueous humor is much less than the compounds identified in our investigation, or it may have been degraded by the isolation and chromatographic purification protocols used in our investigations.

Indexed as

BirdsAnimalsAqueous HumorAscorbic AcidEyeFlight, AnimalUltraviolet RaysAscorbic Acid

Identifiers

PMID33431985
PMCPMC7801516
OpenAlexW3119781117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.