ArticleScientific reports2021
Effect of gravity on brain structure as indicated on upright computed tomography.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 32 citations in OpenAlex.
- Application of upright multidetector CT in orthopedics and the musculoskeletal system: insights into anatomy, alignment, and biomechanics.Japanese journal of radiology · 2026Review
- 3D Freehand Ultrasound Imaging of Optic Nerve Sheath.Investigative radiology · 2026Article
- Effect of body position on cerebral perfusion: a comparison of supine and seated positions assessed using conventional and upright CT perfusion.European radiology experimental · 2026Observational
- Upright multidetector CT with 320-row gantry: a technical innovation providing insights into human anatomy under gravity and potential clinical implications.The British journal of radiology · 2025Article
- Assessing morphological changes in the choroid plexus between standing and supine positions using a rotatable MRI system.Scientific reports · 2025Article
- Comparative analysis of residual setup errors in head and neck patients from upright versus supine radiotherapy postures.Medical physics · 2025Article
- Recent trends in scientific research in chest radiology: What to do or not to do? That is the critical question in research.Japanese journal of radiology · 2025Review
- Automated orofacial virtual patient creation using two cohorts of MSCT vs. CBCT scans.Head & face medicine · 2025Article
- Surgical Outcomes in Chiari 1 and Chiari 1.5 Malformation Treated by Posterior Fossa Reconstruction: A Comprehensive Analysis of 110 Pediatric Cases and Literature Review.Journal of clinical medicine · 2024Article
- Exploration of postural effects on the external jugular and diploic venous system using upright computed tomography scanning.Neuroradiology · 2024Article
- Anatomical changes in the male pelvis between the supine and upright positions-A feasibility study for prostate treatments in the upright position.Journal of applied clinical medical physics · 2023Article
- Anatomical cardiac and electrocardiographic axes correlate in both upright and supine positions: an upright/supine CT study.Scientific reports · 2023Article
- The use of image synthesis techniques in target and roi delineation in the upright position.Journal of applied clinical medical physics · 2023Article
- Estimating right atrial pressure using upright computed tomography in patients with heart failure.European radiology · 2023Article
- Identification of a novel path for cerebrospinal fluid (CSF) drainage of the human brain.PloS one · 2023Article
- Emerging Materials, Wearables, and Diagnostic Advancements in Therapeutic Treatment of Brain Diseases.Biosensors · 2022Review
- [Postdural puncture headache in obstetrics : Pathogenesis, diagnostics and treatment].Die Anaesthesiologie · 2022Article
- Cranial defect and pneumocephalus are associated with significant postneurosurgical positional brain shift: evaluation using upright computed tomography.Scientific reports · 2022Article
- Upright versus supine MRI: effects of body position on craniocervical CSF flow.Fluids and barriers of the CNS · 2021Article
- Full-field MRI measurements of in-vivo positional brain shift reveal the significance of intra-cranial geometry and head orientation for stereotactic surgery.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to use upright computed tomography (CT) to depict posture-related changes in the brain tissue under normal gravity. Thirty-two asymptomatic volunteers underwent upright CT in the sitting position and conventional CT in the supine position on the same day. We compared the shift of the pineal body, cerebellar tonsil, the length of pituitary stalk, optic nerve sheath area and perimeter (ONSA and ONSP, respectively), and lateral ventricular volume between the supine and sitting positions. We also compared shape changes of the cerebrospinal fluid (CSF) spaces at different sites between both positions. In the sitting position, the pineal body shifted 0.68 ± 0.27 mm in the ventral direction and 0.76 ± 0.24 mm in the caudal direction, the length of pituitary stalk decreased by 1.23 ± 0.71 mm, the cerebellar tonsil descended by 2.10 ± 0.86 mm, the right ONSA decreased by 15.21 ± 6.54%, the left ONSA decreased by 15.30 ± 7.37%, the right ONSP decreased by 8.52 ± 3.91%, the left ONSP decreased by 8.20 ± 4.38%, and the lateral ventricular volume decreased by 5.07 ± 3.24% (all P < 0.001). We also observed changes in the shape of CSF spaces with changes in posture. We concluded that the intracranial structure of healthy subjects and volume of ventricles changed according to posture on Earth.
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