Evidence map›Paper›PMID 33431911›Full record

ArticleNature communications2021

3D printing of inherently nanoporous polymers via polymerization-induced phase separation.

Zheqin Dong, Haijun Cui, Haodong Zhang, Fei Wang, Xiang Zhan, Frederik Mayer, Britta Nestler, Martin Wegener, Pavel A Levkin

Abstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

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  6. Tissue-bioelectronics interfaces.Chemical Society reviews · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zheqin DongInstitute of Biological and Chemical Systems-Functional Molecular Systems (IBCS-FMS) Karlsruhe Institute of Technology, 76344, Eggenstein-Leopoldshafen, Germany.ORCID 0000-0003-3589-5433
Haijun CuiInstitute of Biological and Chemical Systems-Functional Molecular Systems (IBCS-FMS) Karlsruhe Institute of Technology, 76344, Eggenstein-Leopoldshafen, Germany.
Haodong ZhangInstitute of Applied Materials - Computational Materials Scsience (IAM-CMS), Karlsruhe Institute of Technology, 76131, Karlsruhe, Germany.
Fei WangInstitute of Applied Materials - Computational Materials Scsience (IAM-CMS), Karlsruhe Institute of Technology, 76131, Karlsruhe, Germany.
Xiang ZhanInstitute for Micro Process Engineering (IMVT), Karlsruhe Institute of Technology, 76344, Eggenstein-Leopoldshafen, Germany.ORCID 0000-0002-2843-3604
Frederik MayerInstitute of Nanotechnology and Institute of Applied Physics, Karlsruhe Institute of Technology, 76128, Karlsruhe, Germany.
Britta NestlerInstitute of Applied Materials - Computational Materials Scsience (IAM-CMS), Karlsruhe Institute of Technology, 76131, Karlsruhe, Germany.
Martin WegenerInstitute of Nanotechnology and Institute of Applied Physics, Karlsruhe Institute of Technology, 76128, Karlsruhe, Germany.
Pavel A LevkinInstitute of Biological and Chemical Systems-Functional Molecular Systems (IBCS-FMS) Karlsruhe Institute of Technology, 76344, Eggenstein-Leopoldshafen, Germany. levkin@kit.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

3D printing offers enormous flexibility in fabrication of polymer objects with complex geometries. However, it is not suitable for fabricating large polymer structures with geometrical features at the sub-micrometer scale. Porous structure at the sub-micrometer scale can render macroscopic objects with unique properties, including similarities with biological interfaces, permeability and extremely large surface area, imperative inter alia for adsorption, separation, sensing or biomedical applications. Here, we introduce a method combining advantages of 3D printing via digital light processing and polymerization-induced phase separation, which enables formation of 3D polymer structures of digitally defined macroscopic geometry with controllable inherent porosity at the sub-micrometer scale. We demonstrate the possibility to create 3D polymer structures of highly complex geometries and spatially controlled pore sizes from 10 nm to 1000 µm. Produced hierarchical polymers combining nanoporosity with micrometer-sized pores demonstrate improved adsorption performance due to better pore accessibility and favored cell adhesion and growth for 3D cell culture due to surface porosity. This method extends the scope of applications of 3D printing to hierarchical inherently porous 3D objects combining structural features ranging from 10 nm up to cm, making them available for a wide variety of applications.

Identifiers

PMID33431911
PMCPMC7801408

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.