ArticleScientific reports2021
Bioactive diterpenoids impact the composition of the root-associated microbiome in maize (Zea mays).
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 60 citations in OpenAlex.
- Dynamic Assembly and Multifunctional Roles of Plant Endophytic Microbiomes.Microorganisms · 2026Review
- Discovery of the rosalexin pathway expands the modular network of maize diterpenoid phytoalexins.Research square · 2026Article
- Distinct Defence Mechanisms of Allelopathic Rice Against Quinclorac-Susceptible and -Resistant Barnyardgrass: Involvement of Specific Metabolites and Rhizosheath Microbiota.Plant biotechnology journal · 2026Article
- Comparative metabolomic analysis of leaves and kernels in wild type andFood chemistry. Molecular sciences · 2026Article
- Genotype-specific root morphology and metabolic traits shape bacterial communities and tolerance to Fusarium root rot in wheat.PloS one · 2026Article
- The role of isoprenoids in the chemical interaction between plants and other organisms in their rhizosphere.aBIOTECH · 2025Review
- Synthetic communities of maize root bacteria interact and redirect benzoxazinoid metabolization.mSphere · 2025Article
- Elucidating the interplay between metabolites and microorganisms in the spermosphere of common bean (mSystems · 2025Article
- Characterization of switchgrass (Panicum virgatum L.) PvKSL1 as a levopimaradiene/abietadiene-type diterpene synthase.Plant biology (Stuttgart, Germany) · 2025Article
- Microbiome Migration from Soil to Leaves in Maize and Rice.Microorganisms · 2025Article
- Diterpenoid Phytoalexins Shape Rice Root Microbiomes and Their Associations With Root Parasitic Nematodes.Environmental microbiology · 2025Article
- Maize stigmas react differently to self- and cross-pollination and fungal invasion.Plant physiology · 2024Article
- The lactonase BxdA mediates metabolic specialisation of maize root bacteria to benzoxazinoids.Nature communications · 2024Article
- Biochar Loaded with a Bacterial Strain N33 Facilitates Pecan Seedling Growth and Shapes Rhizosphere Microbial Community.Plants (Basel, Switzerland) · 2024Article
- Bacterial tolerance to host-exuded specialized metabolites structures the maize root microbiome.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Terpenes modulate bacterial and fungal growth and sorghum rhizobiome communities.Microbiology spectrum · 2023Article
- Anti-fungal bioactive terpenoids in the bioenergy crop switchgrass (Panicum virgatum) may contribute to ecotype-specific microbiome composition.Communications biology · 2023Article
- A dolabralexin-deficient mutant provides insight into specialized diterpenoid metabolism in maize.Plant physiology · 2023Article
- Maize Terpene Synthase 8 (ZmTPS8) Contributes to a Complex Blend of Fungal-Elicited Antibiotics.Plants (Basel, Switzerland) · 2023Article
- Comparative transcriptomics and metabolomics reveal specialized metabolite drought stress responses in switchgrass (Panicum virgatum).The New phytologist · 2022Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Plants deploy both primary and species-specific, specialized metabolites to communicate with other organisms and adapt to environmental challenges, including interactions with soil-dwelling microbial communities. However, the role of specialized metabolites in modulating plant-microbiome interactions often remains elusive. In this study, we report that maize (Zea mays) diterpenoid metabolites with known antifungal bioactivities also influence rhizosphere bacterial communities. Metabolite profiling showed that dolabralexins, antibiotic diterpenoids that are highly abundant in roots of some maize varieties, can be exuded from the roots. Comparative 16S rRNA gene sequencing determined the bacterial community composition of the maize mutant Zman2 (anther ear 2), which is deficient in dolabralexins and closely related bioactive kauralexin diterpenoids. The Zman2 rhizosphere microbiome differed significantly from the wild-type sibling with the most significant changes observed for Alphaproteobacteria of the order Sphingomonadales. Metabolomics analyses support that these differences are attributed to the diterpenoid deficiency of the Zman2 mutant, rather than other large-scale metabolome alterations. Together, these findings support physiological functions of maize diterpenoids beyond known chemical defenses, including the assembly of the rhizosphere microbiome.
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