Evidence map›Paper›PMID 33431854›Full record

ArticleNature communications2021

Optimizing respiratory virus surveillance networks using uncertainty propagation.

Sen Pei, Xian Teng, Paul Lewis, Jeffrey Shaman

Abstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Reconstructing the early spatial spread of pandemic respiratory viruses in the United States.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Toward optimal disease surveillance with graph-based active learning.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sen PeiDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA. sp3449@cumc.columbia.edu.ORCID 0000-0002-7072-2995
Xian TengSchool of Computing and Information, University of Pittsburgh, Pittsburgh, PA, 15260, USA.
Paul LewisIntegrated Biosurveillance Section, Armed Forces Health Surveillance Branch, Silver Spring, MD, 20904, USA.
Jeffrey ShamanDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA. jls106@cumc.columbia.edu.ORCID 0000-0002-7216-7809

Funding

Development and Dissemination of Operational Real-Time Respiratory Virus ForecastU01GM110748 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHAMAN, JEFFREY L · 2014 to 2018
$2.6M
NIGMS NIH HHS U01 GM110748
6 · The paper itself

Abstract

Infectious disease prevention, control and forecasting rely on sentinel observations; however, many locations lack the capacity for routine surveillance. Here we show that, by using data from multiple sites collectively, accurate estimation and forecasting of respiratory diseases for locations without surveillance is feasible. We develop a framework to optimize surveillance sites that suppresses uncertainty propagation in a networked disease transmission model. Using influenza outbreaks from 35 US states, the optimized system generates better near-term predictions than alternate systems designed using population and human mobility. We also find that monitoring regional population centers serves as a reasonable proxy for the optimized network and could direct surveillance for diseases with limited records. The  proxy method is validated using model simulations for 3,108 US counties and historical data for two other respiratory pathogens - human metapneumovirus and seasonal coronavirus - from 35 US states and can be used to guide systemic allocation of surveillance efforts.

Indexed as

UncertaintyCoronavirus InfectionsDisease OutbreaksForecastingHumansInfluenza, HumanModels, StatisticalPopulation Surveillance

Identifiers

PMID33431854
PMCPMC7801666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.