Evidence map›Paper›PMID 33431732›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Vancomycin Intoxication and Cefepime-induced Encephalopathy Treated by Abdominal Drainage of Massive Ascites in Addition to Online Hemodiafiltration.

Tomoki Taniguchi, Yuta Inoue, Mitsuru Itoh, Mayumi Tomita, Tadashi Kamata, Noriyuki Iehara

Open access · diamondAbstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tomoki TaniguchiDepartment of Nephrology, Kyoto City Hospital, Japan.
Yuta InoueDepartment of Hematology, Kyoto City Hospital, Japan.
Mitsuru ItohDepartment of Hematology, Kyoto City Hospital, Japan.
Mayumi TomitaDepartment of Nephrology, Kyoto City Hospital, Japan.
Tadashi KamataDepartment of Nephrology, Kyoto City Hospital, Japan.
Noriyuki IeharaDepartment of Nephrology, Kyoto City Hospital, Japan.
Kyoto City Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A patient with recurrent plasmacytoma with massive ascites exhibited vancomycin intoxication and cefepime-induced encephalopathy due to renal dysfunction. The ascitic accumulation of these drugs was suspected because of the refractory intoxicated state. To remove these drugs that had accumulated in the blood and ascites, abdominal drainage was performed in addition to online hemodiafiltration. If patients with renal dysfunction and massive ascites develop vancomycin intoxication and cefepime-induced encephalopathy that cannot be improved by drug discontinuation, physicians should suspect ascitic accumulation and evaluate the ascitic concentration. Furthermore, if a high accumulation in massive ascites occurs, physicians should perform abdominal drainage along with blood purification.

Indexed as

Brain DiseasesHemodiafiltrationAscitesCefepimeDrainageHumansNeoplasm Recurrence, LocalVancomycinCefepimeVancomycinabdominal drainageAKIcefepime-induced encephalopathyonline hemodiafiltrationvancomycin intoxication

Identifiers

PMID33431732
PMCPMC8222134
OpenAlexW3120139129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.