ArticleProceedings of the National Academy of Sciences of the United States of America2021
Invariant timescale hierarchy across the cortical somatosensory network.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Structure-function dynamics in healthy cognitive aging: a graph signal processing approach.Brain structure & function · 2026Article
- The role of transthalamic pathways in perception.Communications biology · 2026Review
- A doubly stochastic renewal framework for partitioning spiking variability.Nature communications · 2025Article
- Sleep Modulates Neural Timescales and Spatiotemporal Integration in the Human Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Flexibility of intrinsic neural timescales during distinct behavioral states.Communications biology · 2024Article
- Signatures of hierarchical temporal processing in the mouse visual system.PLoS computational biology · 2024Article
- Thalamocortical interactions shape hierarchical neural variability during stimulus perception.iScience · 2024Article
- Interacting ventral temporal gradients of timescales and functional connectivity and their relationships to visual behavior.iScience · 2024Article
- Neural timescales reflect behavioral demands in freely moving rhesus macaques.Nature communications · 2024Article
- Cortical timescales and the modular organization of structural and functional brain networks.Human brain mapping · 2024Article
- Article
- Neural timescales reflect behavioral demands in freely moving rhesus macaques.bioRxiv : the preprint server for biology · 2023Article
- Hierarchical unimodal processing within the primary somatosensory cortex during a bimodal detection task.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- Modular Organization of Signal Transmission in Primate Somatosensory Cortex.Frontiers in neuroanatomy · 2022Article
- Dimensionality reduction and recurrence analysis reveal hidden structures of striatal pathological states.Frontiers in systems neuroscience · 2022Article
- The diversity and specificity of functional connectivity across spatial and temporal scales.NeuroImage · 2021Review
- A continuum of invariant sensory and behavioral-context perceptual coding in secondary somatosensory cortex.Nature communications · 2021Article
- Cognitive flexibility and brain network energy in healthy aging: An allostatic perspective from the SENECA model.Imaging neuroscience (Cambridge, Mass.)Article
- Estimating fMRI timescale maps.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability of cortical networks to integrate information from different sources is essential for cognitive processes. On one hand, sensory areas exhibit fast dynamics often phase-locked to stimulation; on the other hand, frontal lobe areas with slow response latencies to stimuli must integrate and maintain information for longer periods. Thus, cortical areas may require different timescales depending on their functional role. Studying the cortical somatosensory network while monkeys discriminated between two vibrotactile stimulus patterns, we found that a hierarchical order could be established across cortical areas based on their intrinsic timescales. Further, even though subareas (areas 3b, 1, and 2) of the primary somatosensory (S1) cortex exhibit analogous firing rate responses, a clear differentiation was observed in their timescales. Importantly, we observed that this inherent timescale hierarchy was invariant between task contexts (demanding vs. nondemanding). Even if task context severely affected neural coding in cortical areas downstream to S1, their timescales remained unaffected. Moreover, we found that these time constants were invariant across neurons with different latencies or coding. Although neurons had completely different dynamics, they all exhibited comparable timescales within each cortical area. Our results suggest that this measure is demonstrative of an inherent characteristic of each cortical area, is not a dynamical feature of individual neurons, and does not depend on task demands.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.