Evidence map›Paper›PMID 33431672›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

A link between synaptic plasticity and reorganization of brain activity in Parkinson's disease.

Diliana Rebelo, Francisco Oliveira, Antero Abrunhosa, Cristina Januário, João Lemos, Miguel Castelo-Branco

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. The combination of theScientific reports · 2025
    Article
  3. Molecular connectivity studies in neurotransmission: a scoping review.Imaging neuroscience (Cambridge, Mass.) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Diliana RebeloInstitute of Nuclear Sciences Applied to Health, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0003-0279-0221
Francisco OliveiraInstitute of Nuclear Sciences Applied to Health, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0001-9468-8894
Antero AbrunhosaInstitute of Nuclear Sciences Applied to Health, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0002-4145-854X
Cristina JanuárioCoimbra Institute for Biomedical Imaging and Translational Research (CIBIT), University of Coimbra, 3000-548 Coimbra, Portugal.
João LemosCoimbra Institute for Biomedical Imaging and Translational Research (CIBIT), University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0002-9128-7064
Miguel Castelo-BrancoInstitute of Nuclear Sciences Applied to Health, University of Coimbra, 3000-548 Coimbra, Portugal; mcbranco@fmed.uc.pt.ORCID 0000-0003-4364-6373
University of Coimbra · PTChampalimaud Foundation · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The link between synaptic plasticity and reorganization of brain activity in health and disease remains a scientific challenge. We examined this question in Parkinson's disease (PD) where functional up-regulation of postsynaptic D

Indexed as

Neuronal PlasticityAgedBrain MappingCase-Control StudiesCaudate NucleusDopamineDopamine AntagonistsFemaleFrontal LobeHumansMagnetic Resonance ImagingMaleMiddle AgedNeuronsOxygenParietal LobeDopamineDopamine AntagonistsDRD2 protein, humanOxygenRacloprideReceptors, Dopamine D2functional connectivityfunctional magnetic resonance imagingmolecular imagingpositron emission tomography

Identifiers

PMID33431672
PMCPMC7826364
OpenAlexW3119929230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.