Evidence map›Paper›PMID 33431657›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2021

Intestinal IL-17R Signaling Controls Secretory IgA and Oxidase Balance in

Yasuka Matsunaga, Trevon Clark, Alanna G Wanek, Jacob P Bitoun, Qingqing Gong, Misty Good, Jay K Kolls

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. The Safety ofViruses · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yasuka MatsunagaCenter for Translational Research in Infection and Inflammation, Tulane School of Medicine, New Orleans, LA 70112.
Trevon ClarkCenter for Translational Research in Infection and Inflammation, Tulane School of Medicine, New Orleans, LA 70112.
Alanna G WanekCenter for Translational Research in Infection and Inflammation, Tulane School of Medicine, New Orleans, LA 70112.
Jacob P BitounDepartment of Microbiology and Immunology, Tulane School of Medicine, New Orleans, LA 70112; and.ORCID 0000-0001-7110-2328
Qingqing GongDepartment of Pediatrics, Washington University, St Louis, MO 63110.
Misty GoodDepartment of Pediatrics, Washington University, St Louis, MO 63110.ORCID 0000-0002-0264-5721
Jay K KollsCenter for Translational Research in Infection and Inflammation, Tulane School of Medicine, New Orleans, LA 70112; jkolls1@tulane.edu.ORCID 0000-0001-5151-6304
Tulane University · USWashington University in St. Louis · US

Funding

Washington University DDRCC Supplemental Equipment RequestP30DK052574 · NIDDK · WASHINGTON UNIVERSITY · PI Nicholas O. Davidson · 2000 to 2026
$30.8M
Training in CD4 T-cell Lung ImmunityR35HL139930 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI KOLLS, JAY K · 2018 to 2024
$6.3M
The Role of STa in ETEC PathogenesisR01AI125542 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI BITOUN, JACOB P. · 2017 to 2020
$1.5M
Development of an ETEC multivalent subunit vaccine using outer membrane vesiclesR21AI190682 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI Jacob P. Bitoun · 2025 to 2026
$415k
NHLBI NIH HHS R35 HL139930NIAID NIH HHS R01 AI125542NIAID NIH HHS R21 AI190682NIDDK NIH HHS P30 DK052574
6 · The paper itself

Abstract

Type 17 cytokines have been strongly implicated in mucosal immunity, in part by regulating the production of antimicrobial peptides. Using a mouse model of

Indexed as

AnimalsCitrobacter rodentiumDisease Models, AnimalEnterobacteriaceae InfectionsHumansHydrogen PeroxideImmunoglobulin A, SecretoryIntestinal MucosaMiceMice, KnockoutOxidoreductasesReceptors, Interleukin-17Signal TransductionHydrogen PeroxideIl17ra protein, mouseImmunoglobulin A, SecretoryOxidoreductasesReceptors, Interleukin-17

Identifiers

PMID33431657
PMCPMC8663204
OpenAlexW3120989320

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.