Evidence map›Paper›PMID 33431461›Full record

ArticleBMJ case reports2021

Peritoneal melanosis associated with metastatic melanoma previously treated with targeted and immune checkpoint inhibitor therapy.

Kwang Kiat Sim, Katie Connell, Mayank Bhandari, David Paton

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Peritoneal melanosis: case report and literature review.Journal of surgical case reports · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Kwang Kiat SimDepartment of General Surgery, Fiona Stanley Hospital, Murdoch, Western Australia, Australia kwang.sim@health.wa.gov.au.ORCID http://orcid.org/0000-0002-0618-5865
Katie ConnellAnatomical Pathology, Western Diagnostic Pathology, Myaree, Western Australia, Australia.
Mayank BhandariDepartment of General Surgery, Hepatopancreaticobiliary Surgery, Fiona Stanley Hospital, Murdoch, Western Australia, Australia.
David PatonAnatomical Pathology, Western Diagnostic Pathology, Myaree, Western Australia, Australia.
Fiona Stanley Hospital · AUCurtin University · AUPathwest Laboratory Medicine · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peritoneal melanosis is an uncommon benign condition, the pathophysiology of which is unclear. Macroscopically, it appears as diffuse dark brown or black pigmentation within the peritoneum, mimicking more sinister conditions such as metastatic melanoma. It has been described in a variety of contexts, but only exceedingly rarely in association with metastatic melanoma, with only two previous published case reports. We present a case of peritoneal melanosis associated with metastatic melanoma involving the spleen, previously treated with targeted and immune checkpoint inhibitor therapy. With increasing reports of melanoma regression manifesting as cutaneous tumorous melanosis in patients treated with immune checkpoint inhibitors, we postulate that, similarly, immunotherapy and tumour regression might have a role to play in the pathogenesis of the peritoneal pigmentation in this case.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsBiopsyChemotherapy, AdjuvantHumansImmune Checkpoint InhibitorsMaleMelanomaMelanosisMiddle AgedPeritoneal DiseasesPeritoneumPositron-Emission TomographyProtein Kinase InhibitorsSkin NeoplasmsSpleenSplenectomyImmune Checkpoint InhibitorsProtein Kinase Inhibitorsgeneral surgerymalignant disease and immunosuppressionskin cancer

Identifiers

PMID33431461
PMCPMC7802683
OpenAlexW3119804330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.