Evidence map›Paper›PMID 33431287›Full record

ReviewTrends in cognitive sciences2021

The Continuity of Context: A Role for the Hippocampus.

Andrew P Maurer, Lynn Nadel

Abstract readReview
In one paragraph

Review in Trends in cognitive sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Response Flexibility: The Role of the Lateral Habenula.Frontiers in behavioral neuroscience · 2022
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Neural Patterns Reflect Shared Emotional History.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  8. Article
  9. Hippocampal Drift Rate Reflects the Temporal Organization of Memories.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. The Relative Contributions of Traits and Contexts on Social Network Learning.Open mind : discoveries in cognitive science · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrew P MaurerDeparment of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. Electronic address: drewmaurer@ufl.edu.
Lynn NadelDepartment of Psychology and Program in Cognitive Science, University of Arizona, Tucson, AZ, USA. Electronic address: nadel@arizona.edu.

Funding

Testing and forecasting hippocampal theta wave propagation in learning and memoryR01MH109548 · NIMH · UNIVERSITY OF FLORIDA · PI MAURER, ANDREW PORTER · 2016 to 2020
$2.1M
Age-associated changes in hippocampal circuits and cognitive functionR01AG055544 · NIA · UNIVERSITY OF FLORIDA · PI MAURER, ANDREW PORTER · 2017 to 2021
$1.9M
NIA NIH HHS R01 AG055544NIMH NIH HHS R01 MH109548
6 · The paper itself

Abstract

Tracking moment-to-moment change in input and detecting change sufficient to require altering behavior is crucial to survival. Here, we discuss how the brain evaluates change over time, focusing on the hippocampus and its role in tracking context. We leverage the anatomy and physiology of the hippocampal longitudinal axis, re-entrant loops, and amorphous networks to account for stimulus equivalence and the updating of an organism's sense of its context. Place cells have a central role in tracking contextual continuities and discontinuities across multiple scales, a capacity beyond current models of pattern separation and completion. This perspective highlights the critical role of the hippocampus in both spatial cognition and episodic memory: tracking change and detecting boundaries separating one context, or episode, from another.

Indexed as

HippocampusMemory, EpisodicBrainCognitioncontextdynamical systemshippocampuslongitudinal axis

Identifiers

PMID33431287
PMCPMC9617208

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.